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1.3.1.38: trans-2-enoyl-CoA reductase (NADPH)

This is an abbreviated version!
For detailed information about trans-2-enoyl-CoA reductase (NADPH), go to the full flat file.

Wordmap for 1.3.1.38

Word Map on EC 1.3.1.38 Wordmap for 1.3.1.38

Reaction

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acyl-CoA
+
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NADP+
=
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trans-2,3-dehydroacyl-CoA
+
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NADPH
+
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H+

Synonyms

2-trans enoyl-ACP(CoA) reductase, ECR, EgTER1, enoyl reductase, InhA, MECR, MECR-1, mitochondrial 2-trans-enoyl-CoA/ACP reductase, mitochondrial 2-trans-enoyl-thioester reductase, NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, TER, trans-2-enoyl-CoA reductase, trans-2-enoyl-CoA reductase (NADPH)

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                EC 1.3.1.381.3.1.38 trans-2-enoyl-CoA reductase (NADPH)

Disease

Disease on EC 1.3.1.38 - trans-2-enoyl-CoA reductase (NADPH)

for references in articles please use BRENDA:EC1.3.1.38

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Intellectual Disability
Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to change in sphingolipid profile.
Tuberculosis
Selection of an Escherichia coli host that expresses mutant forms of Mycobacterium tuberculosis 2-trans enoyl-ACP(CoA) reductase and 3-ketoacyl-ACP(CoA) reductase enzymes.