1.3.1.34: 2,4-dienoyl-CoA reductase (NADPH)

This is an abbreviated version!
For detailed information about 2,4-dienoyl-CoA reductase (NADPH), go to the full flat file.

Word Map on EC 1.3.1.34

Reaction

trans-2,3-didehydroacyl-CoA
+
NADP+
=
trans,trans-2,3,4,5-tetradehydroacyl-CoA
+
NADPH
+
H+

Synonyms

2,4-dienoyl coenzyme A reductase, 2,4-dienoyl-CoA reductase, 2,4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase, 4-enoyl-CoA reductase (NADPH), 4-enoyl-CoA reductase [NADPH], DCR, DECR, More, pDCR, peroxisomal 2,4-dienoyl CoA reductase, SDR, short-chain dehydrogenase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.34 2,4-dienoyl-CoA reductase (NADPH)

Subunits

Subunits on EC 1.3.1.34 - 2,4-dienoyl-CoA reductase (NADPH)

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SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
-
x * 34000, recombinant truncated His-tagged enzyme, SDS-PAGE
homodimer
-
2 * 34000, SDS-PAGE
homotetramer
-
4 * 36066, immature monomer of the 120 kDa isoform, RT-PCR, PCR-fragment subcloned to pUC18, sequenced
tetramer
-
crystal structure
additional information
-
analytical ultracentrifugation analysis of purified pDCR reveals that the protein exists as a mixture of monomers, dimers, and tetramers in solution