1.3.1.34: 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

This is an abbreviated version!
For detailed information about 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing], go to the full flat file.

Word Map on EC 1.3.1.34

Reaction

a (2E)-2-enoyl-CoA
+
NADP+
=
a (2E,4E)-2,4-dienoyl-CoA
+
NADPH
+
H+

Synonyms

2,4-dienoyl coenzyme A reductase, 2,4-dienoyl-CoA reductase, 2,4-dienoyl-CoA reductase (NADPH), 2,4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase (NADPH), 4-enoyl-CoA reductase [NADPH], DCR, DECR, pDCR, peroxisomal 2,4-dienoyl CoA reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

Specific Activity

Specific Activity on EC 1.3.1.34 - 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0015
mutant enzyme C334A/C337A, with 2-trans,4-trans-decadienoyl-CoA as substrate
0.0067
mutant enzyme C337A, with 2-trans,4-trans-decadienoyl-CoA as substrate
0.007
mutant enzyme H252A, with 2-trans,4-trans-decadienoyl-CoA as substrate
0.095
mutant enzyme E164A, with 2-trans,4-trans-decadienoyl-CoA as substrate
0.33
mutant enzyme H252A/Y166F, with 2-trans,4-trans-decadienoyl-CoA as substrate
1.79
-
2,4-hexadienoyl-CoA, NADPH
10.9
-
2-trans,4-trans-decadienoyl-CoA, NADPH
2.02
mutant enzyme Y166F, with 2-trans,4-trans-decadienoyl-CoA as substrate
3.9
-
2-trans,4-trans-decadienoyl-CoA, NADPH
7.21
-
purified recombinant truncated His-tagged enzyme, substrate 2,4-trans-hexadienoyl-CoA
7.54
wild type enzyme, with 2-trans,4-trans-decadienoyl-CoA as substrate