1.3.1.34: 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

This is an abbreviated version!
For detailed information about 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing], go to the full flat file.

Word Map on EC 1.3.1.34

Reaction

a (2E)-2-enoyl-CoA
+
NADP+
=
a (2E,4E)-2,4-dienoyl-CoA
+
NADPH
+
H+

Synonyms

2,4-dienoyl coenzyme A reductase, 2,4-dienoyl-CoA reductase, 2,4-dienoyl-CoA reductase (NADPH), 2,4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase (NADPH), 4-enoyl-CoA reductase [NADPH], DCR, DECR, pDCR, peroxisomal 2,4-dienoyl CoA reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

KM Value

KM Value on EC 1.3.1.34 - 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0127
(2E,4E)-2,4-decadienoyl-CoA
pH 7.4, 20°C
0.0716
(2E,4E)-2,4-hexadienoyl-CoA
pH 7.4, 20°C
0.102
2,4,7,10,13,16,19-docosaheptaenoyl-CoA
in the absence of albumin
0.006
2,4-decadienoyl-CoA
in the present of 0.1% albumin
0.059
2,4-hexadienoyl-CoA
in the presence of 0.1% albumin
0.0062
2,4-trans-decadienoyl-CoA
-
recombinant His-tagged truncated enzyme, pH 6.0, 22°C
0.0265
2,4-trans-hexadienoyl-CoA
-
recombinant His-tagged truncated enzyme, pH 6.0, 22°C
0.0023
2-trans,4-trans-decadienoyl-CoA
-
-
0.00044 - 0.0605
NADPH
additional information
additional information
-
kinetics of oleoyl-CoA degradation in mitochondrial protein extract
-