1.3.1.34: 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

This is an abbreviated version!
For detailed information about 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing], go to the full flat file.

Word Map on EC 1.3.1.34

Reaction

a (2E)-2-enoyl-CoA
+
NADP+
=
a (2E,4E)-2,4-dienoyl-CoA
+
NADPH
+
H+

Synonyms

2,4-dienoyl coenzyme A reductase, 2,4-dienoyl-CoA reductase, 2,4-dienoyl-CoA reductase (NADPH), 2,4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase (NADPH), 4-enoyl-CoA reductase [NADPH], DCR, DECR, pDCR, peroxisomal 2,4-dienoyl CoA reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

Disease

Disease on EC 1.3.1.34 - 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
2,4-dienoyl-coa reductase [(2e)-enoyl-coa-producing] deficiency
Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis.
[2,4-Dienoyl-CoA reductase deficiency]
Autoimmune Diseases
Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis.
Hypoglycemia
Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis.
Infertility
Comparative testis proteome of cattleyak from different developmental stages.
Prostatic Neoplasms
2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer.