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1.3.1.21: 7-dehydrocholesterol reductase

This is an abbreviated version!
For detailed information about 7-dehydrocholesterol reductase, go to the full flat file.

Word Map on EC 1.3.1.21

Reaction

cholesterol
+
NADP+
=
cholesta-5,7-dien-3beta-ol
+
NADPH
+
H+

Synonyms

3-hydroxysterol DELTA7-reductase, 3beta-hydroxysterol DELTA7-reductase, 3beta-hydroxysterol-DELTA7-reductase, 7-dehydrocholesterol DELTA7 reductase, 7-dehydrocholesterol DELTA7-reductase, 7-DHC reductase, 7-DHCR, Csa7G447780, DAF-36, DELTA5,7-sterol DELTA7-reductase, Des7, Dhcr7, Dhcr7-AS-1, Dhcr7-AS-2, Dhcr7-AS-4, Dwarf5 protein, DWF5, Neverland, Nvd, reductase, 7-dehydrocholesterol, Sterol delta-7-reductase, sterol DELTA7 reductase, sterol DELTA7-reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.21 7-dehydrocholesterol reductase

Natural Substrates Products

Natural Substrates Products on EC 1.3.1.21 - 7-dehydrocholesterol reductase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
7-dehydrodesmosterol + NADPH
desmosterol + NADP+
show the reaction diagram
cholesta-5,7-dien-3-beta-ol + NADPH
cholesterol + NADP+
show the reaction diagram
cholesta-5,7-dien-3beta-ol + NADPH
cholesterol + NADP+
show the reaction diagram
cholesta-5,7-dien-3beta-ol + NADPH + H+
cholesterol + NADP+
show the reaction diagram
-
-
-
-
?
cholesterol + NADP+
cholesta-5,7-dien-3beta-ol + NADPH + H+
show the reaction diagram
cholesterol + O2 + NAD(P)H + H+
cholesta-5,7-dien-3beta-ol + NAD(P)+ + 2 H2O
show the reaction diagram
first committed step in biosynthesis of Caenorhabditis elegans bile acid-like steroids called dafachronic acids
-
-
?
desmosterol + NADP+
7-dehydrodesmosterol + NADPH + H+
show the reaction diagram
ergosta-5,7-diene-3beta-ol + NADPH
ergosta-5-ene-3beta-ol + NADP+
show the reaction diagram
additional information
?
-