1.3.1.21: 7-dehydrocholesterol reductase

This is an abbreviated version!
For detailed information about 7-dehydrocholesterol reductase, go to the full flat file.

Reaction

Synonyms

3-hydroxysterol DELTA7-reductase, 3beta-hydroxysterol DELTA7-reductase, 3beta-hydroxysterol-DELTA7-reductase, 7-dehydrocholesterol DELTA7 reductase, 7-dehydrocholesterol DELTA7-reductase, 7-DHC reductase, 7-DHCR, Csa7G447780, DAF-36, DELTA5,7-sterol DELTA7-reductase, Des7, Dhcr7, Dhcr7-AS-1, Dhcr7-AS-2, Dhcr7-AS-4, Dwarf5 protein, DWF5, Neverland, Nvd, reductase, 7-dehydrocholesterol, Sterol delta-7-reductase, sterol DELTA7 reductase, sterol DELTA7-reductase

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.21 7-dehydrocholesterol reductase

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Results	in table
6	Activating Compound
80	AA Sequence
13	Application
1	CAS Registry Number
22	Cloned(Commentary)
35	Cofactor
550	Disease/ Diagnostics
1	Expression
19	General Information
3	General Stability
7	IC50 Value
113	Inhibitors
7	Ki Value [mM]
4	KM Value [mM]
33	Localization
1	Metals/Ions
5	Molecular Weight [Da]
55	Natural Substrates/ Products (Substrates)
209	Organism
13	Pathway
5	pH Optimum
2	Posttranslational Modification
63	Protein Variants
2	Purification (Commentary)
4	Reaction
3	Reaction Type
70	Reference
75	Source Tissue
7	Specific Activity [micromol/min/mg]
123	Substrates and Products (Substrate)
7	Subunits
57	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]

KI Value

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KI Value on EC 1.3.1.21 - 7-dehydrocholesterol reductase

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Ki VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0014

20,25-Diazacholesterol

Rattus norvegicus

-

-

349269

0.00005

6,7-diaza-5alpha-cholest-8(14)-en-3beta-ol

Zea mays

-

-

349275

0.00007

6-aza-B-homo-5alpha-cholest-7-en-3beta-ol

Zea mays

-

-

349275

0.5

cholest-5,7-dien-3beta-ol

Zea mays

-

-

349275

0.000109 - 0.00024

trans-1,4-Bis-(2-chlorobenzylaminomethyl)cyclohexane dihydrochloride

2 entries

0.047 - 0.083

Triparanol

Rattus norvegicus

-

-

349269

0.000109

trans-1,4-Bis-(2-chlorobenzylaminomethyl)cyclohexane dihydrochloride

Rattus norvegicus

-

-

349274

0.00016 - 0.00024

trans-1,4-Bis-(2-chlorobenzylaminomethyl)cyclohexane dihydrochloride

Rattus norvegicus

-

-

349269