Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.3.1.2: dihydropyrimidine dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about dihydropyrimidine dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.3.1.2

Reaction

5,6-dihydrouracil
+
NADP+
=
Uracil
+
NADPH
+
H+

Synonyms

4,5-dihydrothymine: oxidoreductase, dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate), DHPDH, DHPDHase, DHU dehydrogenase, dihydropyrimidine dehydrogenase, dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, dihydrouracil dehydrogenase (NADP), dihydrouracil dehydrogenase (NADP+), DPD, DPYD, hydropyrimidine dehydrogenase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)

KI Value

KI Value on EC 1.3.1.2 - dihydropyrimidine dehydrogenase (NADP+)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0005
1-deazauracil
-
-
0.0021
3-deazauracil
-
-
0.0066
5,6-dioxyuracil
-
-
0.0048
5-(phenylselenenyl)uracil
-
-
0.0054
5-(phenylthio)uracil
-
-
0.0002
5-benzyloxybenzyluracil
-
-
0.0034
5-benzyluracil
-
-
0.0038
5-nitrobarbituric acid
-
-
0.15
dihydrouracil
-
-
0.001 - 0.011
NADP+
0.007
NADPH
-
-
additional information
additional information
-