1.3.1.14: dihydroorotate dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about dihydroorotate dehydrogenase (NAD+), go to the full flat file.

Word Map on EC 1.3.1.14

Reaction

(S)-dihydroorotate
+
NAD+
=
Orotate
+
NADH
+
H+

Synonyms

More, reductase, orotate, orotate reductase, dihydroorotate dehydrogenase, dihydro-orotic dehydrogenase, L-5,6-dihydro-orotate:NAD oxidoreductase, DHODase, DHO dehydrogenase, dihydrorotate dehydrogenase B, DHOdehase A, b-type dihydroorotate dehydrogenase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.14 dihydroorotate dehydrogenase (NAD+)

Substrates Products

Substrates Products on EC 1.3.1.14 - dihydroorotate dehydrogenase (NAD+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(S)-dihydroorotate + 2,6-dichlorophenolindophenol
orotate + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-
-
-
?
(S)-dihydroorotate + acceptor
orotate + reduced acceptor
show the reaction diagram
(S)-dihydroorotate + NAD+
orotate + NADH + H+
show the reaction diagram
5-fluorodihydroorotate + NAD+
5-fluoroorotate + NADH + H+
show the reaction diagram
-
more active substrate for reverse reaction than orotate
-
-
r
dihydroorotate + acceptor
orotate + reduced acceptor
show the reaction diagram
dihydroorotate + NAD+
orotate + NADH + H+
show the reaction diagram
additional information
?
-