1.3.1.120: cyclohexane-1-carbonyl-CoA reductase (NADP+)

This is an abbreviated version!
For detailed information about cyclohexane-1-carbonyl-CoA reductase (NADP+), go to the full flat file.

Reaction

Synonyms

1-cyclohexenylcarbonyl-CoA reductase, chcA

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.120 cyclohexane-1-carbonyl-CoA reductase (NADP+)

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	AA Sequence
2	Cloned(Commentary)
4	Cofactor
4	General Information
4	Inhibitors
1	Ki Value [mM]
4	KM Value [mM]
1	Localization
5	Metals/Ions
1	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
4	Organism
1	Pathway
2	pH Optimum
2	Purification (Commentary)
1	Reaction
4	Reference
1	Specific Activity [micromol/min/mg]
9	Substrates and Products (Substrate)
2	Subunits
4	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

Systematic Name

print visible entries

print all entries

Systematic Name on EC 1.3.1.120 - cyclohexane-1-carbonyl-CoA reductase (NADP+)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

cyclohexane-1-carbonyl-CoA:NADP+ 1-oxidoreductase

The enzyme, characterized from the bacterium Streptomyces collinus, is involved in a pathway that transforms shikimate to cyclohexane-1-carbonyl-CoA by a series of dehydration and double-bond reduction steps. Most of the steps in this process occur with the carboxylic acid activated as a coenzyme A thioester. The enzyme catalyses three steps in this pathway, also acting on (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carbonyl-CoA and (5S)-5-hydroxycyclohex-1-ene-1-carbonyl-CoA.