EC 1.3.1.114: 3-dehydro-bile acid DELTA4,6-reductase
This is an abbreviated version!
For detailed information about 3-dehydro-bile acid DELTA4,6-reductase, go to the full flat file.
Reaction
Synonyms
BaiN, CLOSCI_00523
ECTree
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26 | AA Sequence |
2 | Cloned(Commentary) |
2 | Cofactor |
4 | General Information |
1 | General Stability |
13 | Natural Substrates/ Products (Substrates) |
2 | Organism |
3 | Pathway |
1 | pH Optimum |
1 | Purification (Commentary) |
4 | Reaction |
2 | Reference |
1 | Storage Stability |
13 | Substrates and Products (Substrate) |
2 | Subunits |
6 | Synonyms |
1 | Systematic Name |
1 | Temperature Optimum [°C] |
Natural Substrates Products
Natural Substrates Products on EC 1.3.1.114 - 3-dehydro-bile acid DELTA4,6-reductase
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REACTION DIAGRAM
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD+
12alpha-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA + NADH + H+
12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NAD+
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
12alpha-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA + NADH + H+
Substrates: -
Products: -
Products: -
?
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD+
12alpha-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA + NADH + H+
Substrates: the enzyme participates in the bile acid 7alpha-dehydroxylation pathway. It catalyses two subsequent reductions of the double bonds within the bile acid A/B rings, following 7alpha-dehydration
Products: -
Products: -
?
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD+
12alpha-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA + NADH + H+
Substrates: -
Products: -
Products: -
?
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD+
12alpha-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA + NADH + H+
Substrates: the enzyme participates in the bile acid 7alpha-dehydroxylation pathway. It catalyses two subsequent reductions of the double bonds within the bile acid A/B rings, following 7alpha-dehydration
Products: -
Products: -
?
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
Substrates: -
Products: -
Products: -
?
12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NAD+
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
Substrates: the enzyme participates in the bile acid 7alpha-dehydroxylation pathway. It catalyses two subsequent reductions of the double bonds within the bile acid A/B rings, following 7alpha-dehydration
Products: -
Products: -
?
12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NAD+
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
Substrates: -
Products: -
Products: -
?
12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NAD+
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
Substrates: the enzyme participates in the bile acid 7alpha-dehydroxylation pathway. It catalyses two subsequent reductions of the double bonds within the bile acid A/B rings, following 7alpha-dehydration
Products: -
Products: -
?
3-oxochol-4,6-dien-24-oyl-CoA + NADH + H+
Substrates: -
Products: -
Products: -
?
3-oxochol-4-en-24-oyl-CoA + NAD+
3-oxochol-4,6-dien-24-oyl-CoA + NADH + H+
Substrates: the enzyme participates in the bile acid 7alpha-dehydroxylation pathway. It catalyses two subsequent reductions of the double bonds within the bile acid A/B rings, following 7alpha-dehydration
Products: -
Products: -
?
3-oxochol-4-en-24-oyl-CoA + NAD+
3-oxochol-4,6-dien-24-oyl-CoA + NADH + H+
Substrates: -
Products: -
Products: -
?
3-oxochol-4-en-24-oyl-CoA + NADH + H+
Substrates: -
Products: -
Products: -
?
3-oxocholan-24-oyl-CoA + NAD+
3-oxochol-4-en-24-oyl-CoA + NADH + H+
Substrates: the enzyme participates in the bile acid 7alpha-dehydroxylation pathway. It catalyses two subsequent reductions of the double bonds within the bile acid A/B rings, following 7alpha-dehydration
Products: -
Products: -
?