caffeoyl-CoA reductase

This is an abbreviated version!
For detailed information about caffeoyl-CoA reductase, go to the full flat file.

Word Map on EC


+ 2 NAD+ + 2 reduced ferredoxin [iron-sulfur] cluster =
+ 2 NADH + 2 oxidized ferredoxin [iron-sulfur] cluster


caffeoyl-CoA reductase-Etf complex, electron-bifurcating caffeoyl-CoA reductase, hydrocaffeoyl-CoA:NAD+, ferredoxin oxidoreductase


     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
       caffeoyl-CoA reductase

Systematic Name

Systematic Name on EC - caffeoyl-CoA reductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments
3-(3,4-dihydroxyphenyl)propanoyl-CoA:NAD+, ferredoxin oxidoreductase
The enzyme, characterized from the bacterium Acetobacterium woodii, contains two [4Fe-4S] clusters and FAD. The enzyme couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant. It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction. It also reduces 4-coumaroyl-CoA and feruloyl-CoA.