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1.3.1.107: sanguinarine reductase

This is an abbreviated version!
For detailed information about sanguinarine reductase, go to the full flat file.

Reaction

dihydrochelirubine
+
NAD(P)+
=
chelirubine
+
NAD(P)H
+
H+

Synonyms

SARED1

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.107 sanguinarine reductase

Engineering

Engineering on EC 1.3.1.107 - sanguinarine reductase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C157A
15.1% of wild-type activity
D158N
47.1% of wild-type activity
DELTA102-114
2.5% of wild-type activity
F162P
22% of wild-type activity
H161A
15.6% of wild-type activity
M166L
64.5% of wild-type activity
S153A
4.0% of wild-type activity