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1.3.1.106: cobalt-precorrin-6A reductase

This is an abbreviated version!
For detailed information about cobalt-precorrin-6A reductase, go to the full flat file.

Reaction

cobalt-precorrin-6B
+
NAD+
=
cobalt-precorrin-6A
+
NADH
+
H+

Synonyms

CbiJ

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.106 cobalt-precorrin-6A reductase

Systematic Name

Systematic Name on EC 1.3.1.106 - cobalt-precorrin-6A reductase

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SYSTEMATIC NAME
IUBMB Comments
cobalt-precorrin-6B:NAD+ oxidoreductase
The enzyme, which participates in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis, catalyses the reduction of the double bond between C-18 and C-19 of cobalt-precorrin-6A. The enzyme from the bacterium Bacillus megaterium has no activity with NADPH. See EC 1.3.1.54, precorrin-6A reductase, for the corresponding enzyme that participates in the aerobic cobalamin biosynthesis pathway.