1.3.1.101: 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]

This is an abbreviated version!
For detailed information about 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H], go to the full flat file.

Reaction

2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate
+ 8 NAD(P)+ =
2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
+ 8 NAD(P)H + 8 H+

Synonyms

2,3-digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, digeranylgeranylglycerophospholipid reductase, Ta0516m

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.101 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]

Reference

Reference on EC 1.3.1.101 - 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Xu, Q.; Eguchi, T.; Mathews, I.I.; Rife, C.L.; Chiu, H.J.; Farr, C.L.; Feuerhelm, J.; Jaroszewski, L.; Klock, H.E.; Knuth, M.W.; Miller, M.D.; Weekes, D.; Elsliger, M.A.; Deacon, A.M.; Godzik, A.; Lesley, S.A.; Wilson, I.A.
Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids
J. Mol. Biol.
404
403-417
2010
Thermoplasma acidophilum (Q9HKS9), Thermoplasma acidophilum
Manually annotated by BRENDA team
Nishimura, Y.; Eguchi, T.
Stereochemistry of reduction in digeranylgeranylglycerophospholipid reductase involved in the biosynthesis of archaeal membrane lipids from Thermoplasma acidophilum
Bioorg. Chem.
35
276-283
2007
Thermoplasma acidophilum (Q9HKS9), Thermoplasma acidophilum
Manually annotated by BRENDA team
Nishimura, Y.; Eguchi, T.
Biosynthesis of archaeal membrane lipids: digeranylgeranylglycerophospholipid reductase of the thermoacidophilic archaeon Thermoplasma acidophilum
J. Biochem.
139
1073-1081
2006
Thermoplasma acidophilum (Q9HKS9), Thermoplasma acidophilum
Manually annotated by BRENDA team