1.3.1.101: 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]

This is an abbreviated version!
For detailed information about 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H], go to the full flat file.

Reaction

2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate
+ 8 NAD(P)+ =
2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
+ 8 NAD(P)H + 8 H+

Synonyms

2,3-digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, digeranylgeranylglycerophospholipid reductase, Ta0516m

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.101 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]

Natural Substrates Products

Natural Substrates Products on EC 1.3.1.101 - 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
show the reaction diagram
2,3-bis-O-geranylgeranyl-sn-glyceryl 1-phosphate + 8 NAD(P)H + 8 H+
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+
show the reaction diagram
the enzyme catalyzes a critical step in the biosynthesis of archaeal membrane lipids. The saturation of hydrocarbon chains confers the ability to resist hydrolysis and oxidation and helps archaea withstand extreme conditions
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