1.3.1.10: enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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For detailed information about enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific), go to the full flat file.

Reaction

Synonyms

1-cyclohexenylcarbonyl coenzyme A reductase, 2-enoyl thioester reductase, 2-trans-enoyl-ACP reductase, acyl-ACP dehydrogenase, beta-ketoacyl reductase, enoyl acyl-carrier-protein reductase, enoyl reductase, enoyl thioester reductase, enoyl-ACP reductase, enoyl-ACP reductase II, enoyl-ACP reductase III, enoyl-ACP-reductase II, enoyl-acyl carrier protein reductase, enoyl-[acyl carrier protein] reductase, enoyl-[acyl-carrier-protein] reductase, ENR, Etr1p, fabG4, FabI, FabK, FabL, Fabl2, More, Mrf1p, NADPH 2-enoyl Co A reductase, reductase, enoyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide phosphate), trans-enoyl-[acyl-carrier-protein] reductase, YgaA

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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Results	in table
1	Activating Compound
679	AA Sequence
1	Application
2	CAS Registry Number
15	Cloned(Commentary)
25	Cofactor
5	Crystallization (Commentary)
1	Expression
5	General Information
1	General Stability
3	IC50 Value
21	Inhibitors
6	Ki Value [mM]
23	KM Value [mM]
3	Localization
9	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
160	Organism
12	Pathway
225	PDB ID
5	pH Optimum
2	pH Range
2	pH Stability
25	Protein Variants
16	Purification (Commentary)
3	Reaction
3	Reaction Type
36	Reference
12	Specific Activity [micromol/min/mg]
3	Storage Stability
80	Substrates and Products (Substrate)
12	Subunits
61	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Temperature Stability [°C]
11	Turnover Number [1/s]

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1.5

Crotonyl-N-acetyl-cysteamine

Staphylococcus aureus

-

wild type enzyme, at 25°C, in 100 mM Na2HPO4 buffer (pH 7.8)

685233

0.038 - 0.51

crotonyl-[acyl-carrier protein]

3 entries

11.6

crotonyl-[Staphylococcus aureus acyl carrier protein]

Staphylococcus aureus

-

wild type enzyme, at 25°C, in 100 mM Na2HPO4 buffer (pH 7.8)

685233

18

dodec-2-enoyl-CoA

Staphylococcus aureus

-

wild type enzyme, at 25°C, in 100 mM Na2HPO4 buffer (pH 7.8)

685233

30.4

dodecenoyl-N-acetyl-cysteamine

Staphylococcus aureus

-

wild type enzyme, at 25°C, in 100 mM Na2HPO4 buffer (pH 7.8)

685233

18.4 - 157.3

dodecenoyl-[Staphylococcus aureus acyl carrier protein]

3 entries

130.2

NADPH

Staphylococcus aureus

-

wild type enzyme, at 25°C, in 100 mM Na2HPO4 buffer (pH 7.8)

685233

0.038

crotonyl-[acyl-carrier protein]

Staphylococcus aureus

-

mutant enzyme Y147F, pH and temperature not specified in the publication

740716

0.038

crotonyl-[acyl-carrier protein]

Staphylococcus aureus

-

mutant enzyme Y147H, pH and temperature not specified in the publication

740716

0.51

crotonyl-[acyl-carrier protein]

Staphylococcus aureus

-

wild type enzyme, pH and temperature not specified in the publication

740716

18.4

dodecenoyl-[Staphylococcus aureus acyl carrier protein]

Staphylococcus aureus

-

mutant enzyme A95V, at 25°C, in 100 mM Na2HPO4 buffer (pH 7.8)

685233

130.2

dodecenoyl-[Staphylococcus aureus acyl carrier protein]

Staphylococcus aureus

-

wild type enzyme, at 25°C, in 100 mM Na2HPO4 buffer (pH 7.8)

685233

157.3

dodecenoyl-[Staphylococcus aureus acyl carrier protein]

Staphylococcus aureus

-

mutant enzyme F204S, at 25°C, in 100 mM Na2HPO4 buffer (pH 7.8)

685233