1.3.1.10: enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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For detailed information about enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific), go to the full flat file.

Word Map on EC 1.3.1.10

1.3.1.10

tuberculosis

mycobacterium

triclosan

isoniazid

aureus

falciparum

antitubercular

polyketide

mycolic

beta-ketoacyl

thioesterase

pfenr

antimycobacterial

diphenyl

antituberculosis

diazaborine

fas-ii

ketoacyl

dehydrase

biocide

anti-tb

malonyl

ketoreductase

transacylase

beta-ketoacyl-acp

catalase-peroxidase

mdr-tb

drug development

Reaction

trans-2,3-dehydroacyl-[acyl-carrier protein]

Synonyms

1-cyclohexenylcarbonyl coenzyme A reductase, 2-enoyl thioester reductase, 2-trans-enoyl-ACP reductase, acyl-ACP dehydrogenase, beta-ketoacyl reductase, enoyl acyl-carrier-protein reductase, enoyl reductase, enoyl thioester reductase, enoyl-ACP reductase, enoyl-ACP reductase II, enoyl-ACP reductase III, enoyl-ACP-reductase II, enoyl-acyl carrier protein reductase, enoyl-[acyl carrier protein] reductase, enoyl-[acyl-carrier-protein] reductase, ENR, Etr1p, fabG4, FabI, FabK, FabL, Fabl2, More, Mrf1p, NADPH 2-enoyl Co A reductase, reductase, enoyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide phosphate), trans-enoyl-[acyl-carrier-protein] reductase, YgaA

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.1 With NAD⁺ or NADP⁺ as acceptor

1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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Results	in table
1	Activating Compound
679	AA Sequence
1	Application
2	CAS Registry Number
15	Cloned(Commentary)
25	Cofactor
5	Crystallization (Commentary)
1	Expression
5	General Information
1	General Stability
3	IC50 Value
21	Inhibitors
6	Ki Value [mM]
23	KM Value [mM]
3	Localization
9	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
160	Organism
12	Pathway
225	PDB ID
5	pH Optimum
2	pH Range
2	pH Stability
25	Protein Variants
16	Purification (Commentary)
3	Reaction
3	Reaction Type
36	Reference
12	Specific Activity [micromol/min/mg]
3	Storage Stability
80	Substrates and Products (Substrate)
12	Subunits
61	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Temperature Stability [°C]
11	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 1.3.1.10 - enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

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0.008

Escherichia coli

crude cell extract

390503

0.066

Streptococcus pneumoniae

390508

0.18

2 entries

0.2

Candida tropicalis

purified recombinant mutant Y79N

656515

0.3

2 entries

0.4

Escherichia coli

purified by chromatography on DEAE-cellulose and Blue sepharose

390503

0.882

Streptomyces collinus

crude Escherichia coli cell extract after overexpression

2.31

purified recombinant wild-type enzyme

656515

3.667

Streptomyces collinus

purified, overexpressed enzyme

390509