1.2.7.3: 2-oxoglutarate synthase

This is an abbreviated version!
For detailed information about 2-oxoglutarate synthase, go to the full flat file.

Reaction

Synonyms

2-ketoglutarate ferredoxin oxidoreductase, 2-oxoglutarate ferredoxin oxidoreductase, 2-oxoglutarate oxidoreductase, 2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating), 2-oxoglutarate:ferredoxin oxidoreductase, alpha-ketoglutarate oxidoreductase, alpha-ketoglutarate synthase, alpha-ketoglutarate-ferredoxin oxidoreductase, CoA-dependent 2-ketoglutarate oxidoreductase, EC 1.2.7.9, FOR enzyme, For(OGOR), forDABGE, KGOR, KOR enzyme, Kor(OGOR), Mmc1_1749, Mmc1_1750, OGOR, OOR, oorDABC

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.7 With an iron-sulfur protein as acceptor

                1.2.7.3 2-oxoglutarate synthase

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Results	in table
1	Activating Compound
5088	AA Sequence
1	CAS Registry Number
7	Cloned(Commentary)
3	Cofactor
1	Crystallization (Commentary)
8	Expression
8	General Information
3	General Stability
4	Inhibitors
21	kcat/KM [mM/s]
1	Ki Value [mM]
26	KM Value [mM]
5	Localization
4	Metals/Ions
21	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
76	Organism
2	Oxidation Stability
13	Pathway
7	pH Optimum
2	pH Range
4	Protein Variants
7	Purification (Commentary)
1	Reaction
3	Reaction Type
29	Reference
1	Source Tissue
9	Specific Activity [micromol/min/mg]
2	Storage Stability
52	Substrates and Products (Substrate)
16	Subunits
59	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
11	Turnover Number [1/s]

Temperature Range

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Temperature Range on EC 1.2.7.3 - 2-oxoglutarate synthase

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TEMPERATURE RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

60 - 90

Hydrogenobacter thermophilus

D3DIA1; D3DIA2; D3DIA3; D3DIA0; Q93RA0, Q9AJM0; Q9AJL9

60°C: about 35% of maximal activity, 90°C: about 50% of maximal activity, recombinant For, the recombinant For enzyme is inactive at room temperature

649630

70 - 95

Thermococcus litoralis

-

inactive below 25°C, drastical increase of activity at 70°C

288466