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1.2.5.3: aerobic carbon monoxide dehydrogenase

This is an abbreviated version!
For detailed information about aerobic carbon monoxide dehydrogenase, go to the full flat file.

Word Map on EC 1.2.5.3

Reaction

CO
+
a quinone
+
H2O
=
CO2
+
a quinol

Synonyms

aerobic Mo/Cu-containing CO dehydrogenase, Carbon monoxide dehydrogenase, CO dehydrogenase, CODH, CoxS, coxSML, CutL, CutM, CutS, EC 1.2.2.4, EC 1.2.3.10, Mo-CODH, Mo-Cu carbon monoxide dehydrogenase, Mo/Cu CODH, MoCu-CODH, molybdenum- and copper-containing carbon monoxide dehydrogenase, molybdenum- and copper-dependent CO dehydrogenase, molybdenum-containing carbon monoxide dehydrogenase, molybdenum-containing CO dehydrogenase, molybdenum-copper carbon monoxide dehydrogenase, molybdenum-copper CO dehydrogenase, molybdenum/copper-containing carbon monoxide dehydrogenase, molybdoenzyme carbon monoxide dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.5 With a quinone or similar compound as acceptor
                1.2.5.3 aerobic carbon monoxide dehydrogenase

Cloned

Cloned on EC 1.2.5.3 - aerobic carbon monoxide dehydrogenase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
genes coxS, coxM, and coxL, DNA and amino acid sequence determination and analysis, sequence comparisons with Aeropyrum pernix strain K1, phylogenetic analysis
genes coxS, coxM, and coxL, recombinant expression of FAD-reconstituted enzyme and of monomeric deflavo medium subunit in Escherichia coli strain BL21(DE3), subcloning in Escherichia coli strain DH5alpha
genes cutM, cutS, and cutL, gene cluster cutMSL, DNA and amino acid sequence determination and anakysis, sequence comparisons, genetic organization
large, medium, and small subunits of CODH are encoded by the structural genes coxL, coxM, and coxS, respectively. They reside on a 128-kb megaplasmid pHCG3, DNA and amino acid sequence determination and analysis, and molecular organization of the coxMSL gene cluster, sequence comparisons
the enzyme is encoded by the coxMSL structural genes in the megaplasmid-localized coxBCMSLDEFGHIK gene cluster
the enzyme is encoded by the megaplasmid-localized coxBCMSLDEFGHIK gene cluster, the cosMSL structural genes encoding the enzyme
-