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1.2.5.1: pyruvate dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about pyruvate dehydrogenase (quinone), go to the full flat file.

Wordmap for 1.2.5.1

Word Map on EC 1.2.5.1 Wordmap for 1.2.5.1

Reaction

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pyruvate
+
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ubiquinone
+
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H2O
=
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acetate
+
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CO2
+
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ubiquinol

Synonyms

EC 1.2.2.2, ECPOX, POX, poxB, POXEC, pqo, pyruvate (quinone) dehydrogenase, pyruvate oxidase, pyruvate oxidase B, pyruvate:quinone oxidoreductase, pyruvate:ubiquinone-8-oxidoreductase, ubiquinione-dependent pyruvate oxidase, ubiquinone-dependent pyruvate oxidase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.5 With a quinone or similar compound as acceptor
                EC 1.2.5.11.2.5.1 pyruvate dehydrogenase (quinone)

Substrates Products

Substrates Products on EC 1.2.5.1 - pyruvate dehydrogenase (quinone)

for references in articles please use BRENDA:EC1.2.5.1

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
pyruvate + 9,10-anthraquinone-2,6-disulfonic acid + H2O
acetate + CO2 + ?
show the reaction diagram
pyruvate + a quinone
acetate + CO2 + a quinol
show the reaction diagram
-
-
-
-
?
pyruvate + dimethylmenoquinone + H2O
acetate + CO2 + dimethylmenoquinol
show the reaction diagram
-
-
-
-
?
pyruvate + ferricyanide
acetate + CO2 + ferrocyanide
show the reaction diagram
-
activity assayed photometrically by monitoring the reduction of 2,6-dichloroindophenol
-
-
?
pyruvate + ferricyanide + H2O
acetate + CO2 + ferrocyanide
show the reaction diagram
pyruvate + ferricytochrome b1 + H2O
acetate + CO2 + ferrocytochrome b1
show the reaction diagram
pyruvate + menaquinone + H2O
acetate + CO2 + menaquinol
show the reaction diagram
-
-
-
-
?
pyruvate + oxidized 2,6-dichloroindophenol
acetate + CO2 + reduced 2,6-dichloroindophenol
show the reaction diagram
-
activity assayed photometrically by monitoring the reduction of 2,6-dichloroindophenol, pH 6.0, 40Ā°C
-
-
?
pyruvate + oxidized 2,6-dichloroindophenol + H2O
acetate + CO2 + reduced 2,6-dichloroindophenol
show the reaction diagram
-
-
-
-
?
pyruvate + quinone + H2O
acetate + CO2 + quinol
show the reaction diagram
-
-
-
-
?
pyruvate + ubiquinol-6 + H2O
acetate + CO2 + ubiquinol-6
show the reaction diagram
-
the natural electron acceptor for the reduced enzyme is a cell-membrane-associated electron transport system including both ubiquinone-6 and cytochrome b1, with oxygen being the terminal electron acceptor
-
-
?
pyruvate + ubiquinone + H2O
acetate + CO2 + ubiquinol
show the reaction diagram
pyruvate + ubiquinone-30 + H2O
acetate + CO2 + ubiquinol-30
show the reaction diagram
-
ubiquinone-30 is rapidly reduced by pyruvate oxidase only in the presence of palmitic acid
-
-
?
pyruvate + ubiquinone-6 + H2O
acetate + CO2 + ubiquinol-6
show the reaction diagram
-
-
-
-
?
pyruvate + ubiquinone-8
acetate + CO2 + ubiquinol-8
show the reaction diagram
pyruvate + ubiquinone-8 + H2O
acetate + CO2 + ubiquinol-8
show the reaction diagram