1.2.5.1: pyruvate dehydrogenase (quinone)
This is an abbreviated version!
For detailed information about pyruvate dehydrogenase (quinone), go to the full flat file.
Word Map on EC 1.2.5.1
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1.2.5.1
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corynebacterium
-
glutamicum
-
flavoprotein
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fed-batch
-
thiamin
-
acetohydroxyacid
-
transaminase
-
volumetric
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2-ketoisovalerate
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isomeroreductase
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l-valine
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ilvbncd
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dihydroxyacid
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l-lactate
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transhydrogenase
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pta-acka
- 1.2.5.1
-
corynebacterium
- glutamicum
- flavoprotein
-
fed-batch
- thiamin
-
acetohydroxyacid
- transaminase
-
volumetric
- 2-ketoisovalerate
-
isomeroreductase
- l-valine
-
ilvbncd
-
dihydroxyacid
- l-lactate
-
transhydrogenase
-
pta-acka
Reaction
Synonyms
EC 1.2.2.2, ECPOX, POX, poxB, POXEC, pqo, pyruvate (quinone) dehydrogenase, pyruvate oxidase, pyruvate oxidase B, pyruvate:quinone oxidoreductase, pyruvate:ubiquinone-8-oxidoreductase, ubiquinione-dependent pyruvate oxidase, ubiquinone-dependent pyruvate oxidase
ECTree
1.2.5.1 pyruvate dehydrogenase (quinone)Advanced search results
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results (Substrates Products
Substrates Products on EC 1.2.5.1 - pyruvate dehydrogenase (quinone)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
pyruvate + dimethylmenoquinone + H2O
acetate + CO2 + dimethylmenoquinol
-
-
-
-
?
pyruvate + ferricyanide
acetate + CO2 + ferrocyanide
-
activity assayed photometrically by monitoring the reduction of 2,6-dichloroindophenol
-
-
?
pyruvate + oxidized 2,6-dichloroindophenol
acetate + CO2 + reduced 2,6-dichloroindophenol
-
activity assayed photometrically by monitoring the reduction of 2,6-dichloroindophenol, pH 6.0, 40°C
-
-
?
pyruvate + oxidized 2,6-dichloroindophenol + H2O
acetate + CO2 + reduced 2,6-dichloroindophenol
-
-
-
-
?
pyruvate + ubiquinol-6 + H2O
acetate + CO2 + ubiquinol-6
-
the natural electron acceptor for the reduced enzyme is a cell-membrane-associated electron transport system including both ubiquinone-6 and cytochrome b1, with oxygen being the terminal electron acceptor
-
-
?
pyruvate + ubiquinone-30 + H2O
acetate + CO2 + ubiquinol-30
-
ubiquinone-30 is rapidly reduced by pyruvate oxidase only in the presence of palmitic acid
-
-
?
pyruvate + 9,10-anthraquinone-2,6-disulfonic acid + H2O
acetate + CO2 + ?
-
-
-
-
?
pyruvate + 9,10-anthraquinone-2,6-disulfonic acid + H2O
acetate + CO2 + ?
-
-
-
-
?
pyruvate + ferricyanide + H2O
acetate + CO2 + ferrocyanide
-
-
-
-
?
pyruvate + ferricyanide + H2O
acetate + CO2 + ferrocyanide
-
addition of 1% lauric acid
-
-
?
pyruvate + ferricyanide + H2O
acetate + CO2 + ferrocyanide
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enzyme also catalyzes the formation of acetoin from pyruvate and acetaldehyde
-
-
?
pyruvate + ferricyanide + H2O
acetate + CO2 + ferrocyanide
-
addition of 1% lauric acid
-
-
?
pyruvate + ferricytochrome b1 + H2O
acetate + CO2 + ferrocytochrome b1
-
-
-
-
?
pyruvate + ferricytochrome b1 + H2O
acetate + CO2 + ferrocytochrome b1
-
the natural electron acceptor for the reduced enzyme is a cell-membrane-associated electron transport system including both ubiquinone-6- and cytochrome b1, with oxygen being the terminal electron acceptor
-
-
?
pyruvate + ubiquinone + H2O
acetate + CO2 + ubiquinol
-
-
-
-
?
pyruvate + ubiquinone + H2O
acetate + CO2 + ubiquinol
-
-
-
-
ir
pyruvate + ubiquinone-8
acetate + CO2 + ubiquinol-8
-
binding to the phospholipid bilayers is essential for PoxB function in vivo, since ubiquinone, the natural electron acceptor of the enzyme, is dissolved within the membfrane lipid bilayer
-
-
?
pyruvate + ubiquinone-8
acetate + CO2 + ubiquinol-8
-
the role of quinones in the pyruvate oxidase system is investigated in this paper
-
-
?
