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1.2.5.1: pyruvate dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about pyruvate dehydrogenase (quinone), go to the full flat file.

Wordmap for 1.2.5.1

Word Map on EC 1.2.5.1 Wordmap for 1.2.5.1

Reaction

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pyruvate
+
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ubiquinone
+
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H2O
=
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acetate
+
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CO2
+
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ubiquinol

Synonyms

EC 1.2.2.2, ECPOX, POX, poxB, POXEC, pqo, pyruvate (quinone) dehydrogenase, pyruvate oxidase, pyruvate oxidase B, pyruvate:quinone oxidoreductase, pyruvate:ubiquinone-8-oxidoreductase, ubiquinione-dependent pyruvate oxidase, ubiquinone-dependent pyruvate oxidase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.5 With a quinone or similar compound as acceptor
                EC 1.2.5.11.2.5.1 pyruvate dehydrogenase (quinone)

Reference

Reference on EC 1.2.5.1 - pyruvate dehydrogenase (quinone)

for references in articles please use BRENDA:EC1.2.5.1

Please use the Reference Search for a specific query.

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Blake, R.; Hager, L.P.
Activation of pyruvate oxidase by monomeric and micellar amphiphiles
J. Biol. Chem.
253
1963-1971
1978
Escherichia coli
Manually annotated by BRENDA team
Williams, F.R.; Hager, L.P.
A crystalline flavin pyruvate oxidase
J. Biol. Chem.
236
PC36-PC37
1961
Escherichia coli
Manually annotated by BRENDA team
Cunningham, C.C.; Hager, L.P.
Crystalline pyruvate oxidase from Escherichia coli. II. Activation by phospholipids
J. Biol. Chem.
246
1575-1582
1971
Escherichia coli
Manually annotated by BRENDA team
Neumann, P.; Weidner, A.; Pech, A.; Stubbs, M.T.; Tittmann, K.
Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from Escherichia coli
Proc. Natl. Acad. Sci. USA
105
17390-17395
2008
Escherichia coli (P07003)
Manually annotated by BRENDA team
Kiuchi, K.; Hager, L.P.
Reconstitution of the lipid-depleted pyruvate oxidase system of Escherichia coli: the palmitic acid effect
Arch. Biochem. Biophys.
233
776-784
1984
Escherichia coli
Manually annotated by BRENDA team
Bertagnolli, B.L.; Hager, L.P.
Role of flavin in acetoin production by two bacterial pyruvate oxidases
Arch. Biochem. Biophys.
300
364-371
1993
Escherichia coli, Pediococcus pseudomonas
Manually annotated by BRENDA team
Koland, J.G.; Miller, M.J.; Gennis, R.B.
Reconstitution of the membrane-bound, ubiquinone-dependent pyruvate oxidase respiratory chain of Escherichia coli with the cytochrome d terminal oxidase
Biochemistry
23
445-453
1984
Escherichia coli
Manually annotated by BRENDA team
Grabau, C.; Cronan, J.E., Jr.
In vivo function of Escherichia coli pyruvate oxidase specifically requires a functional lipid binding site
Biochemistry
25
3748-3751
1986
Escherichia coli
Manually annotated by BRENDA team
Chang, Y.Y.; Cronan, J.E., Jr.
Sulfhydryl chemistry detects three conformations of the lipid binding region of Escherichia coli pyruvate oxidase
Biochemistry
36
11564-11573
1997
Escherichia coli
Manually annotated by BRENDA team
Marchal, D.; Pantigny, J.; Laval, J.M.; Moiroux, J.; Bourdillon, C.
Rate constants in two dimensions of electron transfer between pyruvate oxidase, a membrane enzyme, and ubiquinone (coenzyme Q8), its water-insoluble electron carrier
Biochemistry
40
1248-1256
2001
Escherichia coli
Manually annotated by BRENDA team
Schreiner, M.E.; Riedel, C.; Holatko, J.; Patek, M.; Eikmanns, B.J.
Pyruvate:quinone oxidoreductase in Corynebacterium glutamicum: molecular analysis of the pqo gene, significance of the enzyme, and phylogenetic aspects
J. Bacteriol.
188
1341-1350
2006
Corynebacterium glutamicum
Manually annotated by BRENDA team
Cunningham, C.C.; Hager, L.P.
Reactivation of the lipid-depleted pyruvate oxidase system from Escherichia coli with cell envelope neutral lipids
J. Biol. Chem.
250
7139-7146
1975
Escherichia coli, Escherichia coli K-12
Manually annotated by BRENDA team
Recny, M.A.; Hager, L.P.
Reconstitution of native Escherichia coli pyruvate oxidase from apoenzyme monomers and FAD
J. Biol. Chem.
257
12878-12886
1982
Escherichia coli
Manually annotated by BRENDA team
Carter, K.; Gennis, R.B.
Reconstitution of the Ubiquinone-dependent pyruvate oxidase system of Escherichia coli with the cytochrome o terminal oxidase complex
J. Biol. Chem.
260
10986-10990
1985
Escherichia coli
Manually annotated by BRENDA team
Mather, M.W.; Gennis, R.B.
Kinetic studies of the lipid-activated pyruvate oxidase flavoprotein of Escherichia coli
J. Biol. Chem.
260
16148-16155
1985
Escherichia coli
Manually annotated by BRENDA team
Bertagnolli, B.L.; Hager, L.P.
Activation of Escherichia coli pyruvate oxidase enhances the oxidation of hydroxyethylthiamin pyrophosphate
J. Biol. Chem.
266
10168-10173
1991
Escherichia coli
Manually annotated by BRENDA team
Wang, A.Y.; Chang, Y.Y.; Cronan, J.E., Jr.
Role of the tetrameric structure of Escherichia coli pyruvate oxidase in enzyme activation and lipid binding
J. Biol. Chem.
266
10959-10966
1991
Escherichia coli
Manually annotated by BRENDA team
Grabau, C.; Cronan, J.E., Jr.
Nucleotide sequence and deduced amino acid sequence of Escherichia coli pyruvate oxidase, a lipid-activated flavoprotein
Nucleic Acids Res.
14
5449-5460
1986
Escherichia coli
Manually annotated by BRENDA team
Hamilton, S.E.; Recny, M.; Hager, L.P.
Identification of the high-affinity lipid binding site in Escherichia coli pyruvate oxidase
Biochemistry
25
8179-8183
1986
Escherichia coli, Escherichia coli CG3
Manually annotated by BRENDA team
Buchholz, J.; Schwentner, A.; Brunnenkan, B.; Gabris, C.; Grimm, S.; Gerstmeir, R.; Takors, R.; Eikmanns, B.J.; Blombach, B.
Platform Engineering: Corynebacterium glutamicum with reduced pyruvate dehydrogenase complex activity for improved production of L-lysine, L-valine, and 2-ketoisovalerate
Appl. Environ. Microbiol.
79
5566-5575
2013
Corynebacterium glutamicum, Corynebacterium glutamicum aceE A16
Manually annotated by BRENDA team
Wieschalka, S.; Blombach, B.; Eikmanns, B.J.
Engineering Corynebacterium glutamicum for the production of pyruvate
Appl. Microbiol. Biotechnol.
94
449-459
2012
Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032
Manually annotated by BRENDA team
Ma, C.; Yu, Z.; Lu, Q.; Zhuang, L.; Zhou, S.
Anaerobic humus and Fe(III) reduction and electron transport pathway by a novel humus-reducing bacterium, Thauera humireducens SgZ-1
Appl. Microbiol. Biotechnol.
99
3619-3628
2015
Thauera humireducens, Thauera humireducens SgZ-1
Manually annotated by BRENDA team
Endo, A.; Tanizawa, Y.; Tanaka, N.; Maeno, S.; Kumar, H.; Shiwa, Y.; Okada, S.; Yoshikawa, H.; Dicks, L.; Nakagawa, J.; Arita, M.
Comparative genomics of Fructobacillus spp. and Leuconostoc spp. reveals niche-specific evolution of Fructobacillus spp.
BMC Genomics
16
1117
2015
no activity in Fructobacillus
Manually annotated by BRENDA team
Borisov, V.B.; Verkhovsky, M.I.
Oxygen as acceptor
EcoSal Plus
6
2
2015
Escherichia coli
Manually annotated by BRENDA team
An, T.T.; Picardal, F.W.
Desulfocarbo indianensis gen. nov., sp. nov., a benzoate-oxidizing, sulfate-reducing bacterium isolated from water extracted from a coal bed
Int. J. Syst. Evol. Microbiol.
64
2907-2914
2014
no activity in Desulfocarbo indianensis
Manually annotated by BRENDA team
Li, Z.; Nimtz, M.; Rinas, U.
The metabolic potential of Escherichia coli BL21 in defined and rich medium
Microb. Cell Fact.
13
45
2014
Escherichia coli
Manually annotated by BRENDA team
Ianniello, R.G.; Zotta, T.; Matera, A.; Genovese, F.; Parente, E.; Ricciardi, A.
Investigation of factors affecting aerobic and respiratory growth in the oxygen-tolerant strain Lactobacillus casei N87
PLoS ONE
11
e0164065
2016
Lacticaseibacillus casei, Lacticaseibacillus casei N87
Manually annotated by BRENDA team
Steinsiek, S.; Stagge, S.; Bettenbrock, K.
Analysis of Escherichia coli mutants with a linear respiratory chain
PLoS ONE
9
e87307
2014
Escherichia coli
Manually annotated by BRENDA team
Goris, T.; Schiffmann, C.L.; Gadkari, J.; Schubert, T.; Seifert, J.; Jehmlich, N.; von Bergen, M.; Diekert, G.
Proteomics of the organohalide-respiring Epsilonproteobacterium Sulfurospirillum multivorans adapted to tetrachloroethene and other energy substrates
Sci. Rep.
5
13794
2015
Sulfurospirillum multivorans
Manually annotated by BRENDA team