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1.2.5.1: pyruvate dehydrogenase (quinone)

This is an abbreviated version!
For detailed information about pyruvate dehydrogenase (quinone), go to the full flat file.

Word Map on EC 1.2.5.1

Reaction

pyruvate
+
ubiquinone
+
H2O
=
acetate
+
CO2
+
ubiquinol

Synonyms

EC 1.2.2.2, ECPOX, POX, poxB, POXEC, pqo, pyruvate (quinone) dehydrogenase, pyruvate oxidase, pyruvate oxidase B, pyruvate:quinone oxidoreductase, pyruvate:ubiquinone-8-oxidoreductase, ubiquinione-dependent pyruvate oxidase, ubiquinone-dependent pyruvate oxidase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.5 With a quinone or similar compound as acceptor
                1.2.5.1 pyruvate dehydrogenase (quinone)

Natural Substrates Products

Natural Substrates Products on EC 1.2.5.1 - pyruvate dehydrogenase (quinone)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
pyruvate + a quinone
acetate + CO2 + a quinol
show the reaction diagram
-
-
-
-
?
pyruvate + ferricytochrome b1 + H2O
acetate + CO2 + ferrocytochrome b1
show the reaction diagram
pyruvate + quinone + H2O
acetate + CO2 + quinol
show the reaction diagram
-
-
-
-
?
pyruvate + ubiquinol-6 + H2O
acetate + CO2 + ubiquinol-6
show the reaction diagram
-
the natural electron acceptor for the reduced enzyme is a cell-membrane-associated electron transport system including both ubiquinone-6 and cytochrome b1, with oxygen being the terminal electron acceptor
-
-
?
pyruvate + ubiquinone + H2O
acetate + CO2 + ubiquinol
show the reaction diagram
pyruvate + ubiquinone-6 + H2O
acetate + CO2 + ubiquinol-6
show the reaction diagram
-
-
-
-
?
pyruvate + ubiquinone-8
acetate + CO2 + ubiquinol-8
show the reaction diagram
pyruvate + ubiquinone-8 + H2O
acetate + CO2 + ubiquinol-8
show the reaction diagram