1.2.3.4: oxalate oxidase

This is an abbreviated version!
For detailed information about oxalate oxidase, go to the full flat file.

Word Map on EC 1.2.3.4

Reaction

oxalate
+
O2
+ 2 H+ = 2 CO2 +
H2O2

Synonyms

aero-oxalo dehydrogenase, Germin, Germin GF-2.8, Germin GF-3.8, germin-like oxidase, gl-OXO, GLP2, HvOxo1, oxalate oxidase, oxalate: O2 oxidoreductase, oxalate:oxygen oxidoreductase, oxalic acid oxidase, OXO, OXO-G, OXO1, OXO2, OXO3, OXO4, OxOx, TaOxo1, TaOxo2

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.3 With oxygen as acceptor
                1.2.3.4 oxalate oxidase

Engineering

Engineering on EC 1.2.3.4 - oxalate oxidase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
E216Q
-
mutant exhibits a 200fold loss in decarboxylase activity and a 10fold increase in oxalate oxidase activity
A242E
-
the mutant shows 5% of the wild type oxidase activity
D241A
-
the mutant contains 17% of the Mn2+ content of the recombinant wild type enzyme and 7% of the wild type oxidase activity
N75A
reduced activity to 2.4% of the wild type level
N85A
reduced activity to 0.5% of the wild type level