1.2.3.3: pyruvate oxidase
This is an abbreviated version!
For detailed information about pyruvate oxidase, go to the full flat file.
Word Map on EC 1.2.3.3
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1.2.3.3
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streptococcus
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thiamin
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plantarum
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sanguinis
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pneumococcus
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lipid-activated
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acetohydroxy
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diphosphate-dependent
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phosphotransacetylase
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synthesis
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oralis
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analysis
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medicine
- 1.2.3.3
- streptococcus
- thiamin
- plantarum
- sanguinis
-
pneumococcus
-
lipid-activated
-
acetohydroxy
-
diphosphate-dependent
- phosphotransacetylase
- synthesis
- oralis
- analysis
- medicine
Reaction
Synonyms
acetyl phosphate-producing pyruvate oxidase, phosphate-dependent pyruvate oxidase, POD, POX, POX-2, poxB, PoxF, PyOD, PyrOx, pyruvate oxidase, pyruvate:oxygen-2-oxidoreductase (phosphorylating), pyruvic oxidase, SpxB, SpxB protein
ECTree
1.2.3.3 pyruvate oxidaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 1.2.3.3 - pyruvate oxidase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2 pyruvate + phosphate + 2 O2 + H2O
acetate + acetyl phosphate + 2 CO2 + 2 H2O2
-
-
-
-
?
2 pyruvate + phosphate + 2 O2 + H2O
acetate + acetyl phosphate + 2 CO2 + 2 H2O2
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-
-
-
?
2 pyruvate + phosphate + 2 O2 + H2O
acetate + acetyl phosphate + 2 CO2 + 2 H2O2
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-
-
-
?
2 pyruvate + phosphate + 2 O2 + H2O
acetate + acetyl phosphate + 2 CO2 + 2 H2O2
-
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
preferred substrate
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
-
?
pyruvate + phosphate + O2
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
-
involved in lactate metabolism
-
?
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
-
specifically favors phosphorylysis rather than hydrolysis, decarboxylation step not rate-limiting
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ir
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
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5 step catalytic reaction
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ir
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
-
contribution to attachment to glycoconjugates of nasopharyngeal cell receptor, type II lung cells and human endothelial cells
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?
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
-
-
-
?
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
-
-
-
-
?
pyruvate + phosphate + O2 + H2O
acetyl phosphate + CO2 + H2O2
-
-
-
-
?
additional information
?
-
-
no activity with L-lactare, phosphoenolpyruvate, very low activity with 2-oxobutyrate and oxaloacetate
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-
?
additional information
?
-
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predominant role in the control of acetate production under aerobic conditions
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?
additional information
?
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predominant role in the control of acetate production under aerobic conditions
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-
?
