1.2.1.87: propanal dehydrogenase (CoA-propanoylating)

This is an abbreviated version!
For detailed information about propanal dehydrogenase (CoA-propanoylating), go to the full flat file.

Reaction

propanal
+
CoA
+
NAD+
=
propanoyl-CoA
+
NADH
+
H+

Synonyms

BphJ, CoA-acylating aldehyde dehydrogenase, coenzyme A-acylating aldehyde dehydrogenase, More, PduP, TTHB247

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.87 propanal dehydrogenase (CoA-propanoylating)

Substrates Products

Substrates Products on EC 1.2.1.87 - propanal dehydrogenase (CoA-propanoylating)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetaldehyde + CoA + NAD+
acetyl-CoA + NADH + H+
show the reaction diagram
acetaldehyde + CoA + NADP+
acetyl-CoA + NADPH + H+
show the reaction diagram
BphJ is able to utilize NAD+ and NADP+ with comparable kcat values, but the apparent Km-value for NAD+ is 16fold lower than for NADP+
-
0
?
acetyl-CoA + NADH + H+
acetaldehyde + CoA + NAD+
show the reaction diagram
butanoyl-CoA + NADH + H+
butanal + CoA + NAD+
show the reaction diagram
butyraldehyde + CoA + NAD+
butyryl-CoA + NAD+ + H+
show the reaction diagram
-
-
0
?
isobutyraldehyde + CoA + NAD+
isobutyryl-CoA + NAD+ + H+
show the reaction diagram
-
-
0
?
pentaldehyde + CoA + NAD+
pentanoyl-CoA + NADH + H+
show the reaction diagram
-
-
0
?
propanal + CoA + NAD+
propanoyl-CoA + NADH + H+
show the reaction diagram
-
-
0
?
propanoyl-CoA + NADH + H+
propanal + CoA + NAD+
show the reaction diagram
propionaldehyde + CoA + NAD+
propanoyl-CoA + NADH + H+
show the reaction diagram
additional information
?
-