1.2.1.76: succinate-semialdehyde dehydrogenase (acylating)

This is an abbreviated version!
For detailed information about succinate-semialdehyde dehydrogenase (acylating), go to the full flat file.

Reaction

succinate semialdehyde
+
CoA
+
NADP+
=
succinyl-CoA
+
NADPH
+
H+

Synonyms

Tneu_0421

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.76 succinate-semialdehyde dehydrogenase (acylating)

Expression

Expression on EC 1.2.1.76 - succinate-semialdehyde dehydrogenase (acylating)

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
approximately 10fold downregulated in presence of acetate, 4-hydroxybutyrate, succinate or pyruvate
extracts of autotrophically grown cells exhibit an NADPH-dependent succinyl-CoA reductase activity of 200 nM/min*mg of soluble protein, whereas extracts of heterotrophically grown cells exhibit an activity of 10 nM/min*mg of protein
-