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1.2.1.65: salicylaldehyde dehydrogenase

This is an abbreviated version!
For detailed information about salicylaldehyde dehydrogenase, go to the full flat file.

Wordmap for 1.2.1.65

Word Map on EC 1.2.1.65 Wordmap for 1.2.1.65

Reaction

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Salicylaldehyde
+
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NAD+
+
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H2O
=
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salicylate
+
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NADH
+ 2 H+

Synonyms

NAD+-dependent salicylaldehyde dehydrogenase, NahF, NahV, SAL dehydrogenase, SALD, SALDan, sALDH, salicylaldehyde dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                EC 1.2.1.651.2.1.65 salicylaldehyde dehydrogenase

Inhibitors

Inhibitors on EC 1.2.1.65 - salicylaldehyde dehydrogenase

for references in articles please use BRENDA:EC1.2.1.65

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
-
40% inhibition at 1 mM
2,2'-dipyridyl
-
50% inhibition at 1 mM
2-naphthaldehyde
-
substrate inhibition
3-Chlorobenzaldehyde
-
substrate inhibition
3-Hydroxybenzaldehyde
-
substrate inhibition
4-Chlorobenzaldehyde
-
substrate inhibition
4-nitrobenzaldehyde
-
substrate inhibition
Al3+
inhibits NahF activity by 42%; inhibits NahV activity by 15%
Ba2+
inhibits NahF activity by 62%; inhibits NahV activity by 52%
benzaldehyde
-
substrate inhibition
Ca2+
inhibits NahF activity by 63%; inhibits NahV activity by 35%
Cs+
inhibits NahF activity by 44%; inhibits NahV activity by 69%
Cu2+
inhibits NahF activity by 70%
EDTA
-
50% inhibition at 50 mM
EGTA
-
60% inhibition at 50 mM
Li+
inhibits NahF activity by 50%; inhibits NahV activity by 57%
Mg2+
inhibits NahF activity by 34%; inhibits NahV activity by 36%
Na+
-
inhibitory at higher concentration
NADP+
-
7% inhibition at 5 mM with 5 mM NAD+
Ni2+
inhibits NahF activity by 60%; inhibits NahV activity by 70%
Salicylaldehyde