1.2.1.65: salicylaldehyde dehydrogenase

This is an abbreviated version!
For detailed information about salicylaldehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.65

Reaction

Salicylaldehyde
+
NAD+
+
H2O
=
salicylate
+
NADH
+ 2 H+

Synonyms

NAD+-dependent salicylaldehyde dehydrogenase, NahF, NahV, SAL dehydrogenase, SALD, SALDan, sALDH, salicylaldehyde dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.65 salicylaldehyde dehydrogenase

Inhibitors

Inhibitors on EC 1.2.1.65 - salicylaldehyde dehydrogenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
-
40% inhibition at 1 mM
2,2'-dipyridyl
-
50% inhibition at 1 mM
2-naphthaldehyde
-
substrate inhibition
3-Chlorobenzaldehyde
-
substrate inhibition
3-Hydroxybenzaldehyde
-
substrate inhibition
4-Chlorobenzaldehyde
-
substrate inhibition
4-nitrobenzaldehyde
-
substrate inhibition
Al3+
inhibits NahF activity by 42%; inhibits NahV activity by 15%
Ba2+
inhibits NahF activity by 62%; inhibits NahV activity by 52%
benzaldehyde
-
substrate inhibition
Ca2+
inhibits NahF activity by 63%; inhibits NahV activity by 35%
Cs+
inhibits NahF activity by 44%; inhibits NahV activity by 69%
Cu2+
inhibits NahF activity by 70%
EDTA
-
50% inhibition at 50 mM
EGTA
-
60% inhibition at 50 mM
Li+
inhibits NahF activity by 50%; inhibits NahV activity by 57%
Mg2+
inhibits NahF activity by 34%; inhibits NahV activity by 36%
Na+
-
inhibitory at higher concentration
NADP+
-
7% inhibition at 5 mM with 5 mM NAD+
Ni2+
inhibits NahF activity by 60%; inhibits NahV activity by 70%
Salicylaldehyde