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1.2.1.59: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)

This is an abbreviated version!
For detailed information about glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating), go to the full flat file.

Word Map on EC 1.2.1.59

Reaction

D-glyceraldehyde 3-phosphate
+
phosphate
 +
NAD(P)+
=
3-phospho-D-glyceroyl phosphate
 +
NAD(P)H
 +
H+

Synonyms

cgap, chloroplast glyceraldehyde-3-phosphate dehydrogenase, CjGAPDH, Dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide (phosphate)), GAP, GapA, GapB, GAPC, GAPDH, GAPDH2, GBS GAPDH, glyceraldehyde 3-phosphate dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)), NAD(NADP)-dependent glyceraldehyde-3-phosphate dehydrogenase, NAD(P)-dependent G3P dehydrogenase, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent glyceraldehyde 3-phosphate dehydrogenase, NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent glyceraldehydephosphate dehydrogenase, pcal_0632, phosphorylating glyceraldehyde-3-phosphate dehydrogenase, STK_13560, Triosephosphate dehydrogenase (NAD(P)), Tsac_2486

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)

Temperature Stability

Temperature Stability on EC 1.2.1.59 - glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
22
the purified recombinant enzyme retains more than 60% of its activity even after an incubation of 72 h at room temperature in the presence of 6 M urea
4
the NADH-dependent activity of the chloroplast GAPDH is not affected by incubation at 4°C, for between 1 and 14 h, with either oxidized ADK3 (OxADK3) or ADK3-DELTACP12 at a ratio of 2:1 (dimeric ADK:tetrameric GAPDH)
43
upon heat-treatment, GAPDH becomes denatured and precipitated but ADK3 greatly improves its thermal stability, decreasing its aggregation and protecting its activity at 43°C. This ability is linked to the presence of the CP12-like extension of ADK3 as no protection is observed when this part is removed
75
-
pH 7.0, 30 min, stable