1.2.1.46: formaldehyde dehydrogenase

This is an abbreviated version, for detailed information about formaldehyde dehydrogenase, go to the full flat file.

Reaction

formaldehyde
+
NAD+
+
H2O
=
formate
+
NADH
+ 2 H+

Synonyms

dehydrogenase, formaldehyde, DL-FDH, dlFalDH, dye-linked formaldehyde dehydrogenase, FADH, FALDH, FdDH, FDH, formaldehyde dehydrogenase, NAD+- and glutathione-dependent formaldehyde dehydrogenase, NAD+- and glutathione-independent formaldehyde dehydrogenase, NAD+- and glutathione_dependent formaldehyde dehydrogenase, NAD+-dependent formaldehyde dehydrogenase, NAD-dependent formaldehyde dehydrogenase, NAD-linked formaldehyde dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.46 formaldehyde dehydrogenase

KM Value

KM Value on EC 1.2.1.46 - formaldehyde dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5.9
acetaldehyde
-
-
100
aryl alcohol
-
-
5.5
benzyl alcohol
-
-
0.067 - 119.9
formaldehyde
30
isobutanol
-
-
6.2
Isobutyraldehyde
-
-
4.2
Isopentanol
-
-
10.6
n-butanol
-
-
4
n-Hexanol
-
-
6.5
n-Pentanol
-
-
50
n-Propanol
-
-
0.0033 - 0.5
NAD+
0.002 - 0.011
NADH
47
propionaldehyde
-
-
0.0017 - 2.65
S-hydroxymethylglutathione
0.0048 - 0.16
S-nitrosoglutathione
additional information
additional information
-
Km for NAD+ with various aldehydes and alcohols
-