1.2.1.39: phenylacetaldehyde dehydrogenase

This is an abbreviated version!
For detailed information about phenylacetaldehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.39

Reaction

phenylacetaldehyde
+
NAD+
+
H2O
=
phenylacetate
+
NADH
+ 2 H+

Synonyms

dehydrogenase, phenylacetaldehyde, ebA4954, feaB, NPADH, PAAL dehydrogenase, PAD, PadA, PADH, PDH, PeaE, PeaE protein, phenylacetaldehyde dehydrogenase, styD

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.39 phenylacetaldehyde dehydrogenase

Crystallization

Crystallization on EC 1.2.1.39 - phenylacetaldehyde dehydrogenase

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CRYSTALLIZATION/commentary
ORGANISM
UNIPROT
LITERATURE
purified recombinant His-tagged enzyme, sitting drop vapor diffusion method, mixing of 5-7 mg/ml protein in 10 mM Tris, pH 7.5, and 1 mM 2-mercaptoethanol, with 100-200 mM trisodium citrate, pH 8.5, and 12-16% PEG 3350, at 4°C, X-ray diffraction structure determination and analysis at 2.83 A resolution, molecular replacement using ALDH1, PDB ID 1BXS, as a starting model, model building