1.2.1.27: methylmalonate-semialdehyde dehydrogenase (CoA-acylating)

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For detailed information about methylmalonate-semialdehyde dehydrogenase (CoA-acylating), go to the full flat file.

Reaction

Synonyms

Aldh6a1, dddC, FG99_15390, KES23460, malonate-semialdehyde dehydrogenase, methylmalonate semialdehyde dehydrogenase, methylmalonate semialdehyde dehydrogenase protein, methylmalonate-semialdehyde dehydrogenase, methylmalonic acid semialdehyde dehydrogenase, MGG_01606, MMSADH, MMSDH, MoMSDH, MSDH, NAD-dependent malonate-semialdehyde dehydrogenase, OdoMMSDH, OsALDH6, PA3570, SSO1218

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)

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Results	in table
10477	AA Sequence
1	CAS Registry Number
12	Cloned(Commentary)
28	Cofactor
4	Crystallization (Commentary)
25	Disease/ Diagnostics
3	Expression
22	General Information
9	Inhibitors
3	kcat/KM [mM/s]
1	Ki Value [mM]
55	KM Value [mM]
5	Localization
11	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
40	Organism
7	Pathway
28	PDB ID
7	pH Optimum
5	pH Range
1	pI Value
2	Posttranslational Modification
22	Protein Variants
13	Purification (Commentary)
1	Reaction
4	Reaction Type
30	Reference
17	Source Tissue
2	Specific Activity [micromol/min/mg]
3	Storage Stability
59	Substrates and Products (Substrate)
17	Subunits
53	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
20	Turnover Number [1/s]

Expression

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Expression on EC 1.2.1.27 - methylmalonate-semialdehyde dehydrogenase (CoA-acylating)

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

during infection, e.g. of susceptible rice cv. CO39 and seedlings of the barley cv. Golden Promise, two ALDH genes (MoMSDH and MoDEL) are exclusively upregulated at 48-hpi with MoMSDH showing about 5.8fold increase in expression pattern during the growth of the rice blast fungus in host tissue. The remaining eight Magnaporthe oryzae ALDH genes show low and unaltered expression pattern at all stages of infection

3 entries

during infection, e.g. of susceptible rice cv. CO39 and seedlings of the barley cv. Golden Promise, two ALDH genes (MoMSDH and MoDEL) are exclusively upregulated at 48-hpi with MoMSDH showing about 5.8fold increase in expression pattern during the growth of the rice blast fungus in host tissue. The remaining eight Magnaporthe oryzae ALDH genes show low and unaltered expression pattern at all stages of infection

Pyricularia oryzae

G4MTY9

762976

during infection, e.g. of susceptible rice cv. CO39 and seedlings of the barley cv. Golden Promise, two ALDH genes (MoMSDH and MoDEL) are exclusively upregulated at 48-hpi with MoMSDH showing about 5.8fold increase in expression pattern during the growth of the rice blast fungus in host tissue. The remaining eight Magnaporthe oryzae ALDH genes show low and unaltered expression pattern at all stages of infection

Pyricularia oryzae FGSC 8958

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during infection, e.g. of susceptible rice cv. CO39 and seedlings of the barley cv. Golden Promise, two ALDH genes (MoMSDH and MoDEL) are exclusively upregulated at 48-hpi with MoMSDH showing about 5.8fold increase in expression pattern during the growth of the rice blast fungus in host tissue. The remaining eight Magnaporthe oryzae ALDH genes show low and unaltered expression pattern at all stages of infection

Pyricularia oryzae ATCC MYA-4617

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