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1.2.1.27: methylmalonate-semialdehyde dehydrogenase (CoA-acylating)

This is an abbreviated version!
For detailed information about methylmalonate-semialdehyde dehydrogenase (CoA-acylating), go to the full flat file.

Word Map on EC 1.2.1.27

Reaction

2-Methyl-3-oxopropanoate
+
CoA
+
H2O
+
NAD+
=
propanoyl-CoA
+
HCO3-
+
NADH

Synonyms

Aldh6a1, dddC, FG99_15390, KES23460, malonate-semialdehyde dehydrogenase, methylmalonate semialdehyde dehydrogenase, methylmalonate semialdehyde dehydrogenase protein, methylmalonate-semialdehyde dehydrogenase, methylmalonic acid semialdehyde dehydrogenase, MGG_01606, MMSADH, MMSDH, MoMSDH, MSDH, NAD-dependent malonate-semialdehyde dehydrogenase, OdoMMSDH, OsALDH6, PA3570, SSO1218

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)

Disease

Disease on EC 1.2.1.27 - methylmalonate-semialdehyde dehydrogenase (CoA-acylating)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acquired Immunodeficiency Syndrome
Quality of life of men with AIDS and the model of social determinants of health.
HIV Infections
HIV infection among young black men who have sex with men--Jackson, Mississippi, 2006-2008.
methylmalonate-semialdehyde dehydrogenase (coa-acylating) deficiency
3-Hydroxyisobutyrate aciduria and mutations in the ALDH6A1 gene coding for methylmalonate semialdehyde dehydrogenase.
Clinical, biochemical, mitochondrial, and metabolomic aspects of methylmalonate semialdehyde dehydrogenase deficiency: Report of a fifth case.
Molecular characterization of methylmalonate semialdehyde dehydrogenase deficiency.
Neoplasms
Establishment of Patient-derived Succinate Dehydrogenase-deficient Gastrointestinal Stromal Tumor Models For Predicting Therapeutic Response.
Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome.
Syphilis
Integrating HIV testing into syphilis partner services in Mississippi to improve HIV case finding.
Integrating Human Immunodeficiency Virus Testing Into Syphilis Partner Services in Mississippi to Improve Human Immunodeficiency Virus Case Finding.