1.2.1.26: 2,5-dioxovalerate dehydrogenase

This is an abbreviated version!
For detailed information about 2,5-dioxovalerate dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.26

Reaction

2,5-dioxopentanoate
+
NADP+
+
H2O
=
2-oxoglutarate
+
NADPH
+ 2 H+

Synonyms

2-oxoglutarate semialdehyde dehydrogenase, alpha-ketoglutarate semialdehyde dehydrogenase, alpha-ketoglutaric semialdehyde dehydrogenase, alpha-KGSA dehydrogenase, alphaKGSA dehydrogenase, alphaKGSADH, DopDH, KGSADH, KGSADH-I, KGSADH-II, KGSADH-III, SSO3117, ycbD protein

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.26 2,5-dioxovalerate dehydrogenase

Natural Substrates Products

Natural Substrates Products on EC 1.2.1.26 - 2,5-dioxovalerate dehydrogenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
2,5-dioxopentanoate + NAD(P)+ + H2O
2-oxoglutarate + NAD(P)H
show the reaction diagram
2,5-dioxopentanoate + NADP+ + H2O
2-oxoglutarate + NADPH + 2 H+
show the reaction diagram