1.2.1.26: 2,5-dioxovalerate dehydrogenase

This is an abbreviated version!
For detailed information about 2,5-dioxovalerate dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.26

Reaction

2,5-dioxopentanoate
+
NADP+
+
H2O
=
2-oxoglutarate
+
NADPH
+ 2 H+

Synonyms

2-oxoglutarate semialdehyde dehydrogenase, alpha-ketoglutarate semialdehyde dehydrogenase, alpha-ketoglutaric semialdehyde dehydrogenase, alpha-KGSA dehydrogenase, alphaKGSA dehydrogenase, alphaKGSADH, DopDH, KGSADH, KGSADH-I, KGSADH-II, KGSADH-III, SSO3117, ycbD protein

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.26 2,5-dioxovalerate dehydrogenase

Activating Compound

Activating Compound on EC 1.2.1.26 - 2,5-dioxovalerate dehydrogenase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
D-galactarate
induces KGSADH-II
D-glucarate
induces KGSADH-II
hydroxy-L-proline
induces KGSADH-III
L-arabinose
induces KGSADH-I
NADP+
the enzyme prefers NADP+ over NAD+