1.2.1.19: aminobutyraldehyde dehydrogenase
This is an abbreviated version!
For detailed information about aminobutyraldehyde dehydrogenase, go to the full flat file.
Word Map on EC 1.2.1.19
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1.2.1.19
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badhs
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choline
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osmoprotectant
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1.2.1.8
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spinacia
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2-acetyl-1-pyrroline
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glycinebetaine
-
3-aminopropionaldehyde
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suaeda
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halophyte
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fragrant
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hypochondriacus
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aldh10s
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amaranthus
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liaotungensis
-
jasmine
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basmati
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4-aminobutyrate
-
synthesis
- 1.2.1.19
-
badhs
- choline
-
osmoprotectant
-
1.2.1.8
-
spinacia
-
2-acetyl-1-pyrroline
- glycinebetaine
- 3-aminopropionaldehyde
-
suaeda
-
halophyte
-
fragrant
-
hypochondriacus
- aldh10s
-
amaranthus
-
liaotungensis
-
jasmine
-
basmati
- 4-aminobutyrate
- synthesis
Reaction
Synonyms
4-aminobutanal dehydrogenase, 4-aminobutyraldehyde dehydrogenase, ABAL dehydrogenase, ABALDH, ALDH10A8, ALDH10A9, AMADH, AMADH1, AMADH2, aminoaldehyde dehydrogenase, BADH, betaine aldehyde dehydrogenase, dehydrogenase, aminobutyraldehyde, EC 1.5.1.35, gadbh, gamma-aminobutanal dehydrogenase, gamma-aminobutyraldehyde dehydroganase, gamma-aminobutyraldehyde dehydrogenase, gamma-guanidinobutyraldehyde dehydrogenase, MdAMADH1, MdAMADH2, More, NAD+-aminoaldehyde dehydrogenase, NAD+-dependent aminoaldehyde dehydrogenase, PatD, PsAMADH 1, PsAMADH 2, SlAMADH1, SlAMADH2, YdcW, ZmAMADH1a, ZmAMADH1b, ZmAMADH2
ECTree
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Reference on EC 1.2.1.19 - aminobutyraldehyde dehydrogenase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Jann, A.; Matsumoto, H.; Haas, D.
The fourth arginine catabolic pathway of Pseudomonas aeruginosa [published erratum appears in J Gen Microbiol 1988 Sep;134(Pt 9):2633]
J. Gen. Microbiol.
134
1043-1053
1988
Pseudomonas aeruginosa
Friedrich, B.; Magasanik, B.
Enzymes of agmatine degradation and the control of their synthesis in Klebsiella aerogenes
J. Bacteriol.
137
1127-1133
1979
Klebsiella aerogenes
Shaibe, E.; Metzer, E.; Halpern, Y.S.
Metabolic pathway for the utilization of L-arginine, L-ornithine, agmatine, and putrescine as nitrogen sources in Escherichia coli K-12
J. Bacteriol.
163
933-937
1985
Escherichia coli
Matthies, C.; Mayer, F.; Schink, B.
Fermentative degradation of putrescine by new strictly anaerobic bacteria
Arch. Microbiol.
151
498-505
1989
Acetobacterium woodii, Desulfovibrio vulgaris, Methanospirillum hungatei, Desulfovibrio vulgaris Marburg / DSM 2119, Methanospirillum hungatei M1h
-
Jakoby, W.B.
Enzymes of gamma-aminobutyrate metabolism (bacterial)
Methods Enzymol.
5
765-778
1962
Escherichia coli, Pseudomonas fluorescens
-
Prieto, M.I.; Martin, J.; Balana-Fouce, R.; Garrido-Pertierra, A.
Properties of gamma-aminobutyraldehyde dehydrogenase from Escherichia coli
Biochimie
69
1161-1168
1987
Escherichia coli
Tago, K.; Kurioka, S.; Matsuda, M.
4-Aminobutyraldehyde dehydrogenase activity in rat brain
J. Neurochem.
39
803-809
1982
Rattus norvegicus, Rattus norvegicus Wistar-
Callewaert, D.M.; Rosemblatt, M.S.; Tchen, T.T.
Purification and properties of 4-aminobutanal dehydrogenase from a Pseudomonas species
J. Biol. Chem.
249
1737-1741
1974
Pseudomonas sp.
Jakoby, W.B.; Fredericks, J.
Pyrrolidine and putrescine metabolism: gamma-aminobutyraldehyde dehydrogenase
J. Biol. Chem.
234
2145-2150
1959
Pseudomonas sp., Pseudomonas fluorescens
Gillyon, C.; Haywood, G.W.; Large, P.J.; Nellen, B.; Robertson, A.
Putrescine breakdown in the yeast candida boidinii: subcellular location of some of the enzymes involved and properties of two acetamidoaldehyde dehydrogenases
J. Gen. Microbiol.
133
2477-2485
1987
[Candida] boidinii
-
Yorifuji, T.; Koike, K.; Sakurai, T.; Yokoyama, K.
4-Aminobutyraldehyde and 4-guanidinobutyraldehyde dehydrogenase for arginine degradation in Pseudomonas putida
Agric. Biol. Chem.
50
2009-2016
1986
Pseudomonas putida
-
Prieto-Santos, M.I.; Martin-Checa, J.; Balane-Fouce, R.; Garrido-Pertierra, A.
A pathway for putrescine catabolism in Escherichia coli
Biochim. Biophys. Acta
880
242-244
1986
Escherichia coli
Arnold, L.J.; You, K.; Allison, W.S.; Kaplan, N.O.
Determination of the hydride transfer stereospecificity of nicotinamide adenine dinucleotide linked oxidoreductases by proton magnetic resonance
Biochemistry
15
4844-4849
1976
Pseudomonas sp.
Vanderbilt, A.S.; Gaby, N.S.; Rodwell, V.W.
Intermediates and enzymes between alpha-ketoarginine and gamma-guanidinobutyrate in the L-arginine catabolic pathway of Pseudomonas putida
J. Biol. Chem.
250
5322-5329
1975
Pseudomonas putida
Shaibe, E.; Metzer, E.; Halpern, Y.S.
Control of utilization of L-arginine, L-ornithine, agmatine, and putrescine as nitrogen sources in Escherichia coli K-12
J. Bacteriol.
163
938-942
1985
Escherichia coli
Shimizu, E.; Tabata, Y.; Hayakawa, R.; Yorifuji, T.
Specific measurement of putrescine with putrescine oxidase and aminobutyraldehyde dehydrogenase
Agric. Biol. Chem.
52
2865-2871
1988
Pseudomonas putida
-
Kurys, G.; Shah, P.C.; Kikonyogo, A.; Reed, D.; Ambroziak, W.; Pietruzko, R.
Human aldehyde dehydrogenase, cDNA cloning and primary structure of the enzyme that catalyzes dehydrogenation of 4-aminobutyraldehyde
Eur. J. Biochem.
218
311-320
1993
Homo sapiens
Kang, H.; Cho, Y.D.
The kinetic mechanism and chemical modification of gamma-aminobutyraldehyde dehydrogenase from soybean (glycine max) axes
Korean Biochem. J.
27
526-533
1994
Glycine max
-
Lee, J.E.; Cho, Y.D.
Immunocytochemical and ultrastructural study of localization of the gamma-aminobutyraldehyde dehydrogenase in the bovine brain
Mol. Cells
5
167-170
1995
Bos taurus
-
Testore, G.; Colombatto, S.; Silvagno, F.; Bedino, S.
Purification and kinetic characterization of gamma-aminobutyraldehyde dehydrogenase from rat liver
Int. J. Biochem. Cell Biol.
27
1201-1210
1995
Rattus norvegicus, Rattus norvegicus Wistar-
Testore, G.; Cravanzola, C.; Bedino, S.
Aldehyde dehydrogenase from rat intestinal mucosa: purification and characterization of an isozyme with high affinity for gamma-aminobutyraldehyde
Int. J. Biochem. Cell Biol.
31
777-786
1999
Rattus norvegicus, Rattus norvegicus Wistar-
Tanaka Dagger, K.; Nakai, R.; Sen, K.; Shimizu, E.; Karasawa, D.; Yorifuji, T.
Purification and characterization of aminobutyraldehyde dehydrogenase from Arthrobacter Sp. TMP-1
J. Biochem. Mol. Biol. Biophys.
6
171-175
2002
Arthrobacter sp.
Livingstone, J.R.; Yoshida, I.; Tarui, Y.; Hirooka, K.; Yamamoto, Y.; Tsutui, N.; Hirasawa, E.
Purification and properties of aminoaldehyde dehydrogenase from Avena sativa
J. Plant Res.
115
393-400
2002
Avena sativa
Samsonova, N.N.; Smirnov, S.V.; Novikova, A.E.; Ptitsyn, L.R.
Identification of Escherichia coli K12 YdcW protein as a gamma-aminobutyraldehyde dehydrogenase
FEBS Lett.
579
4107-4112
2005
Escherichia coli (P77674), Escherichia coli, Escherichia coli K12 MG1655 (P77674)
Petrivalsky, M.; Brauner, F.; Luhova, L.; Gagneul, D.; Sebela, M.
Aminoaldehyde dehydrogenase activity during wound healing of mechanically injured pea seedlings
J. Plant Physiol.
164
1410-1418
2007
Pisum sativum (Q8VWZ1), Pisum sativum
Tylichova, M.; Kopecny, D.; Morera, S.; Briozzo, P.; Lenobel, R.; Snegaroff, J.; Sebela, M.
Structural and functional characterization of plant aminoaldehyde dehydrogenase from Pisum sativum with a broad specificity for natural and synthetic aminoaldehydes
J. Mol. Biol.
396
870-882
2010
Pisum sativum (Q8VWZ1), Pisum sativum (Q93YB2), Pisum sativum
Shelp, B.J.; Bozzo, G.G.; Trobacher, C.P.; Zarei, A.; Deyman, K.L.; Brikis, C.J.
Hypothesis/review: contribution of putrescine to 4-aminobutyrate (GABA) production in response to abiotic stress
Plant Sci.
193-194
130-135
2012
Arabidopsis thaliana
Froemmel, J.; Sebela, M.; Demo, G.; Lenobel, R.; Pospisil, T.; Soural, M.; Kopecny, D.
N-acyl-omega-aminoaldehydes are efficient substrates of plant aminoaldehyde dehydrogenases
Amino Acids
47
175-187
2015
Pisum sativum (Q8VWZ1), Pisum sativum (Q93YB2), Pisum sativum
Jorge, J.M.; Leggewie, C.; Wendisch, V.F.
A new metabolic route for the production of gamma-aminobutyric acid by Corynebacterium glutamicum from glucose
Amino Acids
48
2519-2531
2016
Escherichia coli
Yin, Y.; Yang, R.; Wu, J.; Gu, Z.
Partial purification, characterization and cDNA cloning of aminoaldehyde dehydrogenase in germinated soybean (Glycine max L.)
Eur. Food Res. Technol.
237
731-738
2013
Glycine max (U5ILS4)
-
Zarei, A.; Trobacher, C.P.; Shelp, B.J.
NAD+-aminoaldehyde dehydrogenase candidates for 4-aminobutyrate (GABA) and beta-alanine production during terminal oxidation of polyamines in apple fruit
FEBS Lett.
589
2695-2700
2015
Malus domestica (A0A0E3T3B5), Malus domestica (A0A0E3T552), Malus domestica
Kopecny, D.; Koncitikova, R.; Tylichova, M.; Vigouroux, A.; Moskalikova, H.; Soural, M.; Sebela, M.; Morera, S.
Plant ALDH10 family identifying critical residues for substrate specificity and trapping a thiohemiacetal intermediate
J. Biol. Chem.
288
9491-9507
2013
Solanum lycopersicum, Solanum lycopersicum (B6ECN9), Zea mays (C0P9J6), Zea mays (C6KEM4), Zea mays (G5DDC2), Zea mays
Zarei, A.; Trobacher, C.P.; Shelp, B.J.
Arabidopsis aldehyde dehydrogenase 10 family members confer salt tolerance through putrescine-derived 4-aminobutyrate (GABA) production
Sci. Rep.
6
35115
2016
Arabidopsis thaliana (Q9S795), Arabidopsis thaliana (Q9STS1), Arabidopsis thaliana
Hou, Y.; Ren, H.; Wang, K.; Cao, S.; Zheng, Y.; Wei, Y.; Shao, X.; Wang, H.; Xu, F.
Influence of fresh-cut process on gamma-aminobutyric acid (GABA) metabolism and sensory properties in carrot
J. Food Sci. Technol.
59
552-561
2022
Daucus carota
-
Liu, Y.; Song, Y.; Zeng, S.; Patra, B.; Yuan, L.; Wang, Y.
Isolation and characterization of a salt stress-responsive betaine aldehyde dehydrogenase in Lycium ruthenicum Murr
Physiol. Plant.
163
73-87
2018
Lycium ruthenicum (A0A1P8VFW6), Lycium ruthenicum (A0A1P8VFW8), Lycium ruthenicum
Kanwal, S.; Incharoensakdi, A.
GABA synthesis mediated by gamma-aminobutanal dehydrogenase in Synechocystis sp. PCC6803 with disrupted glutamate and alpha-ketoglutarate decarboxylase genes
Plant Sci.
290
110287
2020
Synechocystis sp. PCC 6803
Xie, K.; Wu, C.; Chi, Z.; Wang, J.; Wang, H.; Wei, Y.; Shao, X.; Xu, F.
Enhancement of gamma-aminobutyric acid (GABA) and other health-promoting metabolites in germinated broccoli by mannose treatment
Sci. Hortic.
276
109706
2021
Brassica oleracea var. italica
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