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1.2.1.19: aminobutyraldehyde dehydrogenase

This is an abbreviated version!
For detailed information about aminobutyraldehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.19

Reaction

4-aminobutanal
+
NAD+
 +
H2O
=
4-aminobutanoate
 +
NADH
 +
H+

Synonyms

4-aminobutanal dehydrogenase, 4-aminobutyraldehyde dehydrogenase, ABAL dehydrogenase, ABALDH, ALDH10A8, ALDH10A9, AMADH, AMADH1, AMADH2, aminoaldehyde dehydrogenase, BADH, betaine aldehyde dehydrogenase, dehydrogenase, aminobutyraldehyde, EC 1.5.1.35, gadbh, gamma-aminobutanal dehydrogenase, gamma-aminobutyraldehyde dehydroganase, gamma-aminobutyraldehyde dehydrogenase, gamma-guanidinobutyraldehyde dehydrogenase, MdAMADH1, MdAMADH2, More, NAD+-aminoaldehyde dehydrogenase, NAD+-dependent aminoaldehyde dehydrogenase, PatD, PsAMADH 1, PsAMADH 2, SlAMADH1, SlAMADH2, YdcW, ZmAMADH1a, ZmAMADH1b, ZmAMADH2

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.19 aminobutyraldehyde dehydrogenase

Inhibitors

Inhibitors on EC 1.2.1.19 - aminobutyraldehyde dehydrogenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2-dimethyl-4-propionylaminobutanal
causes substrate inhibition at high concentration
2-Carboxy-2'-hydroxy-5'-sulfoformazylbenzene
-
zincon
2-mercaptoethanol
66% inhibition at 1 mM
3-aminopropanal
substrate inhibition; substrate inhibition
3-methyl-3-butyrylaminopropanal
causes substrate inhibition at high concentration
3-methyl-4-butyrylaminobutanal
causes substrate inhibition at high concentration
3-propionylaminopropanal
causes substrate inhibition at high concentration
4-acetamidobutanal
causes substrate inhibition at high concentration
4-aminobutanal
substrate inhibition
4-guanidinobutyraldehyde
substrate inhibition; substrate inhibition
4-propionylaminobutanal
causes substrate inhibition at high concentration
acetaldehyde
-
strongly inhibits 4-aminobutyraldehyde oxidation
Ba2+
30% inhibition at 1 mM
Cationic buffers
-
-
-
Cu2+
complete inhibition at 1 mM
EGTA
7.5% inhibition at 1 mM
Hg2+
62% inhibition at 1 mM
iodoacetamide
-
-
ion-exchange resins
-
-
-
L-cysteine
59% inhibition at 1 mM
Mg2+
70% inhibition at 1 mM
monoiodoacetate
-
slowly
N,N,N-trimethyl-4-aminobutyraldehyde
substrate inhibition; substrate inhibition
N-ethylmaleimide
Ni2+
complete inhibition at 1 mM
p-chloromercuribenzoate
-
-
Pb2+
complete inhibition at 1 mM
Zn2+
92% inhibition at 1 mM
additional information
-