Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.2.1.104: pyruvate dehydrogenase system

This is an abbreviated version!
For detailed information about pyruvate dehydrogenase system, go to the full flat file.

Reaction

pyruvate
+
CoA
+
NAD+
=
acetyl-CoA
+
CO2
+
NADH

Synonyms

aceE, AceF, At1g54220, At3g13930, At3g52200, CTHT_0006350, CTHT_0069820, dihydrolipoamide acetyltransferase, dihydrolipoyllysine-residue acetyltransferase component, DLAT, DLD, DLST, E1 component of pyruvate dehydrogenase complex, E1 component subunit alpha, E1 component subunit beta, IAR4, LpdA, Lta3, MAB1, More, Mrp-3, Pda1, Pda1p, PDC, PDCp, PDH, PDH complex, PDH-E1 catalytic subunit, PDHa, PdhA1, PDHalpha, PdhB1, PDHC, PdhE, PDHE1alpha1, PdhH, PdhX, PH2, plastidial pyruvate dehydrogenase complex, pyruvate decarboxylase, pyruvate dehydrogenase, pyruvate dehydrogenase alpha subunit, pyruvate dehydrogenase complex, pyruvate dehydrogenase E1

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.104 pyruvate dehydrogenase system

Molecular Weight

Molecular Weight on EC 1.2.1.104 - pyruvate dehydrogenase system

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
1000000
and 2000000, gel filtration, enzyme isolated from mitochondria-enriched high sedimentation rate fraction
154000
-
-
182000 - 183000
-
light scattering
190000
-
sedimentation equilibrium centrifugation
2000000
206000
-
scanning transmission electron microscopy
230000
gel filtration, mammalian E1p, mE1palpha (PDHA1) and mE1pbeta (PDHB1), and mE3 components are detected mostly in sub-megadalton size fractions of the high ionic strength fraction
230000 - 440000
gel filtration, enzyme isolated from nuclei-enriched low sedimentation rate fraction
35000
36000
37000
38000
40000
-
alpha2,beta2, 2 * 43000 + 2 * 40000, SDS-PAGE, immunoblotting
41000
42000
43000
45000
50000
-
60 * 41000 (E1 alpha) + 60 * 36000 (E1 beta) + 60 * 52000 (E2, EC 2.3.1.12) + 12 * 55000 (E3, EC 1.8.1.4) + 8-12 * 50000 (component X) + kinase and phosphatase components, heart pyruvate dehydrogenase complex
52000
-
60 * 41000 (E1 alpha) + 60 * 36000 (E1 beta) + 60 * 52000 (E2, EC 2.3.1.12) + 12 * 55000 (E3, EC 1.8.1.4) + 8-12 * 50000 (component X) + kinase and phosphatase components, heart pyruvate dehydrogenase complex
55000
-
60 * 41000 (E1 alpha) + 60 * 36000 (E1 beta) + 60 * 52000 (E2, EC 2.3.1.12) + 12 * 55000 (E3, EC 1.8.1.4) + 8-12 * 50000 (component X) + kinase and phosphatase components, heart pyruvate dehydrogenase complex
56000
-
alpha2,beta2, 2 * 38000 + 2 * 56000, SDS-PAGE, N-terminal amino acid sequencing
92500
-
x * 92500, SDS-PAGE
94000
-
2 * 94000, SDS-PAGE
99474
-
2 * 99474, calculation from nucleotide sequence
additional information