1.14.19.B8: [peptidyl-carrier-protein SgcC2]-(3S)-beta-tyrosyl thioester 3-halogenase
This is an abbreviated version!
For detailed information about [peptidyl-carrier-protein SgcC2]-(3S)-beta-tyrosyl thioester 3-halogenase, go to the full flat file.
Reaction
Synonyms
SgcC3
ECTree
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Natural Substrates Products on EC 1.14.19.B8 - [peptidyl-carrier-protein SgcC2]-(3S)-beta-tyrosyl thioester 3-halogenase
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REACTION DIAGRAM
S-(3S)-beta-tyrosyl-[peptidyl-carrier-protein SgcC2]-L-cysteine + 2 FADH2 + 2 H+ + Cl- + O2
S-(S3)-3-chloro-beta-tyrosyl-[peptidyl-carrier-protein SgcC2]-L-cysteine + FAD + 2 H2O
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the enzyme is involved in the biosynthesis of the (S)-3-chloro-5-hydroxy-beta-tyrosine moiety prior to incorporation into the chromoprotein antitumor antibiotic C-1027
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