Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.19.6: acyl-CoA (9+3)-desaturase

This is an abbreviated version!
For detailed information about acyl-CoA (9+3)-desaturase, go to the full flat file.

Word Map on EC 1.14.19.6

Reaction

oleoyl-CoA
+ 2 ferrocytochrome b5 +
O2
 + 2 H+ =
linoleoyl-CoA
 + 2 ferricytochrome b5 + 2 H2O

Synonyms

acyl-CoA (9+3)-desaturase, acyl-lipid DELTA12-desaturase, Cofad2-2, CSFAD2A, D12Des, DELTA 12 desaturase, delta 12 fatty acid desaturases, delta-12 fatty acid desaturase, delta-12 fatty acid desaturase 2, DELTA12 acyl-lipid desaturase, DELTA12 desaturase, DELTA12 FAD, DELTA12 fatty acid desaturase, DELTA12 oleate hydroxylase, DELTA12(omega6)-desaturase, DELTA12-acyl-lipid desaturase, DELTA12-desaturase, DELTA12-desaturase system, DELTA12-FAD, DELTA12-fatty acid desaturase, DELTA12-fatty acyl-CoA desaturase, DELTA12des, DELTA12DS, Des12, DesA, egFAD2, FAD-2, FAD2, FAD2-2, FAD2A, FADS1, FADS2, FAH, FAT-2, fatty acid desaturase-2, Fm2, KlFAD2, Le-FAD2, LKFAD15, microsomal Delta-12 fatty acid desaturase, microsomal delta-12 oleate desaturase, microsomal oleate desaturase, microsomal omega-6 fatty acid desaturase, oleoyl coenzyme A desaturase, oleoyl-CoA DELTA12 desaturase, oleoyl-DELTA12 desaturase, oleoyl-DELTA12/linoleoyl-DELTA3 desaturase, omega-6 fatty acid desaturase, PtFAD2, PtFAD6, seed-specific delta-12 fatty acid desaturase 2

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.6 acyl-CoA (9+3)-desaturase

Expression

Expression on EC 1.14.19.6 - acyl-CoA (9+3)-desaturase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
expression of FAD6 increases fourfold at 4°C compared to expression at 25°C. FAD6 transcription is sensitive to saline stress with a 20fold increase at 6% NaCl
FAD2 mRNA accumulates in leaf mesophyll cells and in root epidermis cells when exposed to 15°C for 4 days in dark conditions
induction of FAD2 expression following a 24 h incubation at 10°C is light dependent, no difference in FAD2 expression is found in plants grown between 32°C and 20°C
mRNA accumulation shows a periodic behaviour, decreasing to the 22°C levels following a 48 h incubation and re-establishing ist 24 h induction after 96 h
no enhancement of enzyme transcript is observed when cells are incubated in the dark at 22°C
shifting of the Mucor rouxii culture from anaerobic to aerobic conditions upregulates levels of expressions of the DELTA9-, DELTA12- and DELTA6-desaturases genes, overview. The transcriptional response is rapid and transient, with the maximal mRNA levels between 0.5 h and 1.0 h after the shift
-
the induction of FAD2 is inhibited by incubation at 10°C under dark conditions but appears unaffected by light intensity
the level of the enzyme transcript increases 10fold within 1 h upon a decrease in temperature from 36°C to 22°C