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1.14.19.3: acyl-CoA 6-desaturase

This is an abbreviated version!
For detailed information about acyl-CoA 6-desaturase, go to the full flat file.

Word Map on EC 1.14.19.3

Reaction

alpha-linolenoyl-CoA
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
stearidonoyl-CoA
+ 2 ferricytochrome b5 + 2 H2O

Synonyms

acyl-CoA DELTA6-desaturase, acyl-CoA desaturase, acyl-CoA-dependent DELTA6-desaturase, AsD6DES, D6 desaturase, d6-des, D6D, D6Des, DEALTA6I, delta 6 desaturase, DELTA 6-desaturase, delta 6-fatty acid desaturase, DELTA-6 desaturase, delta-6 fatty acid desaturase, DELTA-6-desaturase, DELTA6 desaturase, DELTA6 fatty acid desaturase, DELTA6 fatty acyl desaturase, DELTA6-acyl CoA desaturase, DELTA6-acyl-group desaturase, DELTA6-desaturase, DELTA6-desaturase II, DELTA6-fatty acid desaturase, DELTA6-fatty acyl-CoA desaturase, delta61, DELTA6fad_b, DES6, desaturase, fatty acid DA6-, desaturase, linoleate, DesI, EaD6DES, EC 1.14.99.25, FA desaturase 2, FADS2, FADS6, fadsd6, FAT-3, fatty acid 6-desaturase, fatty acid DA6-desaturase, fatty acid DELTA 6-desaturase, fatty acid delta-6 desaturase, fatty acid DELTA6-desaturase, fatty acid desaturase 2, fatty acid desaturase-2, GcFADS2, linoleate desaturase, linoleic acid desaturase, linoleic desaturase, linoleoyl CoA desaturase, linoleoyl-coenzyme A desaturase, long-chain fatty acid DELTA6-desaturase, MaFADS6, MaFADS6-I, Md6, MpFADS6, PiDesD6, TpFADS2

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.3 acyl-CoA 6-desaturase

Activating Compound

Activating Compound on EC 1.14.19.3 - acyl-CoA 6-desaturase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
bovine serum albumin
-
1-10 mg/ml, stimulates enzyme activity of unwashed microsomes by 50%
-
catalase
-
NADH-cytochrome b5 reductase
-
EC 1.6.2.2, absolutely essential for DELTA6-desaturation
-
NADPH-cytochrome b5 reductase
-
EC 1.6.2.2, absolutely essential for DELTA6-desaturation
-
O2
-
absolutely essential for DELTA6-desaturation