acyl-CoA 15-desaturase

This is an abbreviated version!
For detailed information about acyl-CoA 15-desaturase, go to the full flat file.

Word Map on EC


reduced acceptor
+ 2 H2O


bifunctional DELTA12/DELTA15-fatty acid desaturase, CpFAD2, CpFAD3, CsFAD3, CSFAD3A, DELTA 15 desaturase, DELTA-12/DELTA-15 desaturase, DELTA12-desaturase, DELTA12-fatty acid desaturase, DELTA15 desaturase, DELTA15 fatty acid desaturase, DELTA15-fatty acid desaturase, DELTA15D, DES3, EhDES15, FAD3, FAD3-1, FAD3-2, FAD3-3, FAD3A, linoleate DELTA15desaturase, More, omega-3 desaturase, RKD12


     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
       acyl-CoA 15-desaturase

Systematic Name

Systematic Name on EC - acyl-CoA 15-desaturase

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IUBMB Comments
acyl-CoA,reduced acceptor:oxygen oxidoreductase (15,16 cis-dehydrogenating)
The enzyme, characterized from the the plant Sorghum bicolor, is involved in the biosynthesis of sorgoleone, an allelopathic compound produced in root hair cells. The enzyme inserts a cis double bond at carbon 15. When acting on its natural substrate, (9Z,12Z)-hexadeca-9,12-dienoyl-CoA, it produces a product with a terminal double bond.