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1.14.19.10: icosanoyl-CoA 5-desaturase

This is an abbreviated version!
For detailed information about icosanoyl-CoA 5-desaturase, go to the full flat file.

Word Map on EC 1.14.19.10

Reaction

icosanoyl-CoA
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
(Z)-icos-5-enoyl-CoA
+ 2 ferricytochrome b5 + 2 H2O

Synonyms

acyl-CoA DELTA5 desaturase, Delta-5 acyl-CoA desaturase, DELTA5 desaturase, DELTA5DS

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.10 icosanoyl-CoA 5-desaturase

Substrates Products

Substrates Products on EC 1.14.19.10 - icosanoyl-CoA 5-desaturase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+
(Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
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-
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-
?
additional information
?
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very long chain fatty acids are desaturated at the DELTA5 position
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?