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1.14.18.6: 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase

This is an abbreviated version!
For detailed information about 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase, go to the full flat file.

Word Map on EC 1.14.18.6

Reaction

a phytoceramide
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
a (2'R)-2'-hydroxyphytoceramide
+ 2 ferricytochrome b5 +
H2O

Synonyms

FA2H, AtFAH1, FA2H, FAH1, fatty acid 2-hydroxylase, fatty acid 2-hydroxylase 1, fatty acid alpha-hydroxylase, SCS7, Scs7p, scScs7p, sphingolipid alpha-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.18.6 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase

Natural Substrates Products

Natural Substrates Products on EC 1.14.18.6 - 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
a phytoceramide + 2 ferrocytochrome b5 + O2 + 2 H+
a (2'R)-2'-hydroxyphytoceramide + 2 ferricytochrome b5 + H2O
show the reaction diagram
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