1.14.18.5: sphingolipid C4-monooxygenase

This is an abbreviated version!
For detailed information about sphingolipid C4-monooxygenase, go to the full flat file.

Word Map on EC 1.14.18.5

Reaction

a dihydroceramide
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
a (4R)-4-hydroxysphinganine ceramide
+ 2 ferricytochrome b5 +
H2O

Synonyms

bifunctional sphingolipid D4-desaturase/C4-hydroxylase, DES2, DHS hydroxylase, dihydroceramide hydrolase, dihydroceramide hydroxylase, LmjF_26_1670, SBH1, SBH2, SC4H, sphinganine C4-hydroxylase, sphinganine C4-monooxygenase, sphingolipid C4-hydroxylase, sphingolipid delta(4)-desaturase/C4-monooxygenase, sphingolipid hydroxylase, SUR2, Sur2p, SYR2, Syr2p

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.18.5 sphingolipid C4-monooxygenase

Sequence

Sequence on EC 1.14.18.5 - sphingolipid C4-monooxygenase

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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
Sequence
DEGS2_BOVIN
323
0
37319
Swiss-Prot
DEGS2_CAEEL
362
3
42316
Swiss-Prot
DEGS2_HUMAN
323
1
37197
Swiss-Prot
DEGS2_MOUSE
323
0
37491
Swiss-Prot
DEGS2_RAT
323
5
37441
Swiss-Prot
SBH1_ARATH
260
3
29819
Swiss-Prot
SBH2_ARATH
259
3
29831
Swiss-Prot
A0A2P6PRK1_ROSCH
260
4
29756
TrEMBL
A0A2G9I2U3_9LAMI
263
1
30289
TrEMBL
A0A072VZX3_MEDTR
255
5
29296
TrEMBL
A0A084G5A8_9PEZI
377
2
42936
TrEMBL
A0A2P6PAH8_ROSCH
243
2
28067
TrEMBL
A0A2P6R2X2_ROSCH
257
2
29476
TrEMBL
A0A396JTI8_MEDTR
140
2
16019
TrEMBL
A0A2G9HHX5_9LAMI
263
3
30326
TrEMBL
A0A2P6P827_ROSCH
139
2
15524
TrEMBL
A0A2P6P809_ROSCH
118
0
13713
TrEMBL
SUR2_YEAST
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
349
0
40734
Swiss-Prot
Q6YGT5_WICCI
325
0
38334
TrEMBL