1.14.18.2: CMP-N-acetylneuraminate monooxygenase
This is an abbreviated version!
For detailed information about CMP-N-acetylneuraminate monooxygenase, go to the full flat file.
Reaction
+ 2 ferrocytochrome b5 + + 2 H+ = + 2 ferricytochrome b5 +
Synonyms
CMAH, CMP Neu5Ac hydroxylase, CMP-N-acetylneuraminate hydroxylase, CMP-N-acetylneuraminate,NAD(P)H:oxygen oxidoreductase (hydroxylating), CMP-N-acetylneuraminic acid hydroxylase, CMP-Neu5Ac hydroxylase, CMP-NeuAc hydroxylase, cytidine monophosphate-N-acetylneuraminic acid hydroxylase, cytidine monophospho-N-acetylneuraminic acid hydroxylase, EC 1.14.13.45, oxygenase, cytidine monophosphoacetylneuraminate mono-, pcmah
ECTree
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Application
Application on EC 1.14.18.2 - CMP-N-acetylneuraminate monooxygenase
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analysis
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enzyme is used for the detection of human cancer like colon cancer, melanoma, retinoblastoma cell lines and tissues, germ cell tumours and breast cancer by detection of N-glycolylneuraminic acid-containing glycolipids
medicine
C1K3L2
the results pinpoint the crucial need for totally xenofree culturing and expansion conditions for human therapeutic stem cells
synthesis
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enzyme CMAH can be used for large-scale production of N-glycolylneuraminic acid