1.14.18.1: tyrosinase

This is an abbreviated version, for detailed information about tyrosinase, go to the full flat file.

Reaction

2 L-dopa +

O2
= 2 dopaquinone + 2 H2O

Synonyms

AbPPO1, AbPPO4, AbTYR, aurone synthase, catalase-phenol oxidase, catechol oxidase, catecholase, CATPO, chlorogenic acid oxidase, chlorogenic oxidase, cresolase, cresolase/monophenolase, CsPPO, CZA14Tyr, deoxy-tyrosinase, dihydroxy-L-phenylalanine:oxygen oxidoreductase, Diphenol oxidase, diphenolase, dopa oxidase, EC 1.10.3.1, Hc-derived phenoloxidase, Hc-phenoloxidase, HcPO, HdPO, hemocyanin-derived phenoloxidase, jrPPO1, jrTYR, L-DOPA monophenolase, L-DOPA oxidase, L-DOPA:oxygen oxidoreductase, L-tyrosine hydroxylase, MdPPO1, melC2, MelC2 tyrosinase, met-tyrosinase, monophenol dihydroxyphenylalanine:oxygen oxidoreductase, monophenol monooxidase, monophenol monooxygenase, monophenol monoxygenase, monophenol oxidase, monophenol oxygen oxidoreductase, monophenol, 3,4-dihydroxy L-phenylalanine (L-DOPA):oxygen oxidoreductase, monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase, monophenol, dihydroxy-L-phenylalanine:oxygen oxidoreductase, monophenol, dihydroxyphenylalanine:oxygen oxidoreductase, monophenol, L-Dopa: oxidoreductase, monophenol, L-DOPA: oxygen oxidoreductase, monophenol, o-diphenol: oxygen oxidoreductase, monophenol, o-diphenol:O2 oxidoreductase, monophenol, o-diphenol:oxygen oxido-reductase, monophenol, o-diphenol:oxygen oxidoreductase, monophenol, polyphenol oxidase, monophenol: dioxygen oxidoreductases, hydroxylating, monophenolase, monphenol mono-oxgenase, More, mTyr, murine tyrosinase, mushroom tyrosinase, mushroom tyrosine, N-acetyl-6-hydroxytryptophan oxidase, o-diphenol oxidase, o-diphenol oxidoreductase, o-diphenol oxygen oxidoreductase, o-diphenol: O2 oxidoreductase, o-diphenol: oxidoreductase, o-diphenol:O2 oxidoreductase, o-diphenol:oxygen oxidoreductase, o-diphenolase, OCA1, Orf13, oxygen oxidoreductase, phenol oxidase, phenol oxidases, phenolase, phenoloxidase, PO, polyaromatic oxidase, polyphenol oxidase, polyphenol oxidase 3, polyphenol oxidase 4, polyphenol oxidase B, polyphenolase, polyphenoloxidase, PotPPO, PPO, PPO 3, PPO B, PPO1, PPO2, PPO3, pro-PO III, prophenoloxidase III, pyrocatechol oxidase, SPRTyr, ST94, ST94t, tryosinase, tryrosinase, TY, tyr, TYR1, TYR2, tyrA, TyrBm, tyrosinase, tyrosinase 2, tyrosinase 4, tyrosinase diphenolase, tyrosine-dopa oxidase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.18.1 tyrosinase

IC50 Value

IC50 Value on EC 1.14.18.1 - tyrosinase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.035
(+)-gallocatechin-3-O-gallate
Agaricus bisporus;
-
competitive inhibition
0.034
(-)-epigallocatechin-3-O-gallate
Agaricus bisporus;
-
competitive inhibition
0.25
(1E,4E)-1,5-bis(2-fluoro-4-methoxyphenyl)penta-1,4-dien-3-one
Agaricus bisporus;
-
IC50 above 0.25 mM
0.25
(1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-one
Agaricus bisporus;
-
IC50 above 0.25 mM
0.25
(1E,4E)-1,5-bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one
Agaricus bisporus;
-
IC50 above 0.25 mM
0.298
(2-([4-(4-methoxy-benzyloxy)-benzylidene]-hydrazono)-4-oxothiazolidin-5-ylidene)-acetic acid methyl ester
Agaricus bisporus;
-
pH 6.8, 25°C, substrate L-DOPA
0.0498
(2-[(5-methyl-furan-2-ylmethylene)-hydrazono]-4-oxothiazolidin-5-ylidene)-acetic acid methyl ester
Agaricus bisporus;
-
pH 6.8, 25°C, substrate L-DOPA
1
(2E)-3-(3,4-dihydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide
Agaricus bisporus;
-
IC50 above 1 mM
0.35
(2E)-3-(3,4-dihydroxyphenyl)-N-(4-hydroxybenzyl)prop-2-enamide
Agaricus bisporus;
-
-
1
(2E)-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dihydroxyphenyl)ethyl]prop-2-enamide
Agaricus bisporus;
-
IC50 above 1 mM
0.6
(2E)-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enamide
Agaricus bisporus;
-
-
0.25
(2E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enamide
Agaricus bisporus;
-
-
0.028 - 0.2781
(2E)-3-(3,4-dihydroxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide
0.3218
(2E)-3-(3,4-dimethoxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 7.0), at 37°C
1
(2E)-3-(4-chlorophenyl)-N-[2-(4-chlorophenyl)ethyl]prop-2-enamide
Agaricus bisporus;
-
IC50 above 1 mM
0.35
(2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide
Agaricus bisporus;
-
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.03
(2E)-3-(4-hydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide
Agaricus bisporus;
-
-
0.5
(2E)-3-(4-hydroxyphenyl)prop-2-enoic acid
Agaricus bisporus;
-
-
1
(2E)-3-(4-methoxyphenyl)-N-(1-phenylethyl)prop-2-enamide
Agaricus bisporus;
-
IC50 above 1 mM
1
(2E)-3-(4-methoxyphenyl)-N-(2-phenylethyl)prop-2-enamide
Agaricus bisporus;
-
IC50 above 1 mM
0.42
(2E)-3-(4-methoxyphenyl)prop-2-enoic acid
Agaricus bisporus;
-
-
0.1
(2E)-3-phenyl-N-(1-phenylethyl)prop-2-enamide
Agaricus bisporus;
-
IC50 above 0.1 mM
0.1
(2E)-3-phenyl-N-(2-phenylethyl)prop-2-enamide
Agaricus bisporus;
-
IC50 above 0.1 mM
2.1
(2E)-3-phenylprop-2-enoic acid
Agaricus bisporus;
-
-
12.05 - 20
(2E)-but-2-enoic acid
0.35
(2E)-N-(3,4-dihydroxybenzyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide
Agaricus bisporus;
-
-
0.1
(2E)-N-(4-chlorobenzyl)-3-phenylprop-2-enamide
Agaricus bisporus;
-
IC50 above 0.1 mM
0.25
(2E)-N-benzyl-3-(3,4-dihydroxyphenyl)prop-2-enamide
Agaricus bisporus;
-
-
0.028
(2E)-N-benzyl-3-(4-hydroxyphenyl)prop-2-enamide
Agaricus bisporus;
-
-
1
(2E)-N-benzyl-3-(4-methoxyphenyl)prop-2-enamide
Agaricus bisporus;
-
IC50 above 1 mM
0.1
(2E)-N-benzyl-3-phenylprop-2-enamide
Agaricus bisporus;
-
IC50 above 0.1 mM
0.1
(2E)-N-[2-(4-chlorophenyl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide
Agaricus bisporus;
-
IC50 above 0.1 mM
1
(2E)-N-[2-(4-chlorophenyl)ethyl]-3-phenylprop-2-enamide
Agaricus bisporus;
-
IC50 above 1 mM
0.0054
(2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.008 - 0.216
(2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide
0.008
(2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.0238
(2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-methoxyphenyl)prop-2-enamide
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.0404
(2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-phenylprop-2-enamide
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.9 - 4.95
(2E,4E)-hexa-2,4-dienoic acid
0.25
(2E,6E)-2,6-bis[(4-chlorophenyl)methylidene]cyclohexanone
Agaricus bisporus;
-
IC50 above 0.25 mM
0.25
(2E,6E)-2,6-bis[(4-hydroxyphenyl)methylidene]cyclohexanone
Agaricus bisporus;
-
IC50 above 0.25 mM
0.24
(2R,3R)-taxifolin
Agaricus bisporus;
-
-
0.35
(2Z)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid
Agaricus bisporus;
-
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.35
(2Z)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid
Agaricus bisporus;
-
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.1152
(2Z)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.35
(2Z)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid
Agaricus bisporus;
-
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.35
(2Z)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Agaricus bisporus;
-
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.1213
(2Z)-3-(4-hydroxyphenyl)prop-2-enoic acid
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.35
(2Z)-3-(4-methoxyphenyl)prop-2-enoic acid
Agaricus bisporus;
-
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.35
(2Z)-3-phenylprop-2-enoic acid
Agaricus bisporus;
-
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.0501
(4-oxo-2-[(1H-pyrrol-2-ylmethylene)-hydrazono]-thiazolidin-5-ylidene)-acetic acid methyl ester
Agaricus bisporus;
-
pH 6.8, 25°C, substrate L-DOPA
0.208
(4-oxo-2-[(3-phenyl-allylidene)-hydrazono]-thiazolidin-5-ylidene)-acetic acid methyl ester
Agaricus bisporus;
-
pH 6.8, 25°C, substrate L-DOPA
1.85
(S)-imperanene
Homo sapiens;
-
nearly as effective as arbutin
0.07905
1,5-bis(4-hydroxyphenyl)-1,4-pentadiene-3-one
Agaricus bisporus;
-
-
0.00015
1-(1,4-diacetylphenyl)dithiosemicarbazide
Agaricus bisporus;
-
-
0.022
1-(1-(2,4,6-trihydroxyphenyl)ethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00058
1-(1-(2,4-dihydroxyphenyl)ethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00052
1-(1-(4-bromophenyl)ethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00017
1-(1-(4-fluorophenyl)ethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00031
1-(1-(4-hydroxyphenyl)ethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.001
1-(1-(4-isopropylphenyl)ethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00011
1-(1-(4-methoxyphenyl)ethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00042
1-(1-(4-methoxyphenyl)propan-2-ylidene)-thiosemicarbazide
Agaricus bisporus;
-
-
0.00042
1-(1-(4-methoxyphenyl)propan-2-ylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00088
1-(1-(pyrazin-2-yl)ethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00082
1-(1-(pyridin-3-yl)ethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00014
1-(1-(thiophen-2-yl)ethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00027
1-(1-p-tolylethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00034
1-(1-phenylethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00024 - 0.012
1-(2,4-dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)propane
0.00085
1-(2,5-dimethyl-1H-pyrrol-1-yl)thiourea
Agaricus bisporus;
-
-
0.0555
1-(2-hydroxy-1,2-diphenylethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.1
1-(2-oxo-1,2-diphenylethylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00062
1-(3-methylbutylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.0151
1-(3-oxocyclohexylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.0027
1-(3-phenylallylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00054
1-(4-(4-hydroxyphenyl)butan-2-ylidene)-thiosemicarbazide
Agaricus bisporus;
-
-
0.00054
1-(4-(4-hydroxyphenyl)butan-2-ylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.0027
1-(4-bromophenyl)-3-hydroxyurea
Agaricus bisporus;
-
-
0.99
1-(4-fluorophenyl)-ethanone
Agaricus bisporus;
-
-
2
1-(4-methoxyphenyl)-ethanone
Agaricus bisporus;
-
-
0.0115
1-(4-methylpent-3-en-2-ylidene) thiosemicarbazide
Agaricus bisporus;
-
-
0.001
1-(but-2-enylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.00028
1-(butan-2-ylidene)thiosemicarbazide
Agaricus bisporus;
-
-
0.000086 - 0.00011
1-(propan-2-ylidene)thiosemicarbazide
0.15
1-(thiophen-2-yl)-ethanone
Agaricus bisporus;
-
-
0.00095
1-cyclohexylidenethiosemicarbazide
Agaricus bisporus;
-
-
0.000075 - 0.0006
1-cyclopentyl-1-hydroxy-2-oxohydrazine
0.00017
1-cyclopentylidenethiosemicarbazide
Agaricus bisporus;
-
-
0.00026 - 0.0022
1-dodecyl-1-hydroxy-2-oxohydrazine
0.00023
1-ethylidenethiosemicarbazide
Agaricus bisporus;
-
-
0.77
1-hydroxy-1-methyl-3-(4-nitrophenyl)urea
Agaricus bisporus;
-
-
0.0062 - 0.046
1-hydroxy-1-naphthalen-1-yl-2-oxohydrazine
0.00013 - 0.0011
1-hydroxy-2-oxo-1-phenylhydrazine
0.041
1-hydroxy-3-(4-hydroxyphenyl)urea
Agaricus bisporus;
-
-
0.032
1-hydroxy-3-(4-methoxyphenyl)urea
Agaricus bisporus;
-
-
0.0026
1-hydroxy-3-(4-nitrophenyl)urea
Agaricus bisporus;
-
-
0.00029
1-hydroxy-3-phenylurea
Agaricus bisporus;
-
-
0.0043
1-hydroxy-3-[4-(trifluoromethyl)phenyl]urea
Agaricus bisporus;
-
-
0.026
1-methoxy-3-naphthalen-2-ylthiourea
Agaricus bisporus;
-
-
0.0803
1-methylethyl (2E)-3-(5-hydroxy-4-oxo-4H-pyran-2-yl)prop-2-enoate
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.8), at 37°C
0.0078
1-pentanoyl-3-(2,3-dichlorophenyl)thiourea
Agaricus bisporus;
-
pH 6.8, 25°C
0.0197
1-pentanoyl-3-(2,4,6-trimethylphenyl)thiourea
Agaricus bisporus;
-
pH 6.8, 25°C
0.0101
1-pentanoyl-3-(2,4-dinitrophenyl)thiourea
Agaricus bisporus;
-
pH 6.8, 25°C
0.0195
1-pentanoyl-3-(2,6-dibromo-4-fluorophenyl)thiourea
Agaricus bisporus;
-
pH 6.8, 25°C
0.0166
1-pentanoyl-3-(3-nitrophenyl)thiourea
Agaricus bisporus;
-
pH 6.8, 25°C
0.0065
1-pentanoyl-3-(4-bromo-2-fluorophenyl)thiourea
Agaricus bisporus;
-
pH 6.8, 25°C
0.0034
1-pentanoyl-3-(4-bromophenyl)thiourea
Agaricus bisporus;
-
pH 6.8, 25°C
0.0023
1-pentanoyl-3-(4-chlorophenyl)thiourea
Agaricus bisporus;
-
pH 6.8, 25°C
0.0016
1-pentanoyl-3-(4-methoxyphenyl)thiourea
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.008
1-pentanoyl-3-(4-nitrophenyl)thiourea
Agaricus bisporus;
-
pH 6.8, 25°C
0.0002
1-propylidenethiosemicarbazide
Agaricus bisporus;
-
-
0.000086
1-[1-(4-methoxyphenyl)ethylidene]thiosemicarbazide
Agaricus bisporus;
-
-
0.0063
1-[4-(benzyloxy)phenyl]-3-hydroxyurea
Agaricus bisporus;
-
-
0.07
1-[[tert-butyl(dimethyl)silyl]oxy]-3-phenylurea
Agaricus bisporus;
-
-
0.068
1H-indol-5-ol
Mus musculus;
-
-
0.582
2'-(3,4-dihydroxyphenyl)-3',5,5',7,7'-pentahydroxy-2-(4-hydroxyphenyl)-2,2',3,3',4a,8a-hexahydro-4H,4'H-3,8'-bichromene-4,4'-dione
Agaricus bisporus;
-
-
0.0694
2,2':4',2''-ter-1,3,4-oxadiazole-5,5',5''(4H,4''H)-trithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.0029
2,2':4',2''-ter-1,3,4-thiadiazole-5,5',5''(4H,4''H)-trithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.0431 - 0.0461
2,3,4'-trihydroxy-4-methoxydeoxybenzoin
0.3 - 0.5
2,3,4,4'-tetrahydroxydeoxybenzoin
0.2033 - 0.3
2,3,4-trihydroxy-4'-methoxydeoxybenzoin
0.2613 - 0.3
2,4,4',6-tetrahydroxydeoxybenzoin
0.1359 - 0.1785
2,4,4'-trihydroxydeoxybenzoin
0.08435 - 0.1974
2,4,5-trihydroxy-4'-methoxydeoxybenzoin
0.07105 - 0.2302
2,4,6-trihydroxy-4'-methoxydeoxybenzoin
0.1121 - 0.2397
2,4-dihydroxy-3',4'-dimethoxydeoxybenzoin
0.0788 - 0.1814
2,4-dihydroxy-4'-methoxydeoxybenzoin
0.55
2,4-dihydroxy-N-(3,4,5-trihydroxybenzyl)benzamide
Agaricus bisporus;
-
IC50: 0.550 mM
1.82
2,4-dihydroxy-N-(4-hydroxybenzyl)benzamide
Agaricus bisporus;
-
IC50: 1.820 mM
0.042
2,4-dihydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]benzamide
Mus musculus;
-
-
0.00045
2-(2-furanylmethylene)-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.0265
2-(2-hydroxyethoxy)ethyl (2E)-3-(5-hydroxy-4-oxo-4H-pyran-2-yl)prop-2-enoate
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.8), at 37°C
0.0591
2-(2-methoxyethoxy)ethyl (2E)-3-(5-hydroxy-4-oxo-4H-pyran-2-yl)prop-2-enoate
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.8), at 37°C
0.16
2-(3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hydroxyethyl 3,4,5-trihydroxybenzoate
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8) for 10 min at 25°C
0.12
2-(4-fluorophenyl)-quinazolin-4(3H)-one
Agaricus bisporus;
-
pH and temperature not specified in the publication
-
0.0309
2-(4-formyl-2-methoxyphenoxy)-2-oxoethyl (2E)-3-(4-chlorophenyl)prop-2-enoate
Agaricus bisporus;
-
pH 6.8, 25°C
0.0161
2-(4-formyl-2-methoxyphenoxy)-2-oxoethyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate
Agaricus bisporus;
-
pH 6.8, 25°C
0.0426
2-(4-formyl-2-methoxyphenoxy)-2-oxoethyl 2,4-dihydroxybenzoate
Agaricus bisporus;
-
pH 6.8, 25°C
0.1569
2-(4-formyl-2-methoxyphenoxy)-2-oxoethyl 3,4-dihydroxybenzoate
Agaricus bisporus;
-
pH 6.8, 25°C
0.0598
2-(4-formyl-2-methoxyphenoxy)-2-oxoethyl 3,5-dihydroxybenzoate
Agaricus bisporus;
-
pH 6.8, 25°C
0.2012
2-(4-formyl-2-methoxyphenoxy)-2-oxoethyl 4-hydroxybenzoate
Agaricus bisporus;
-
pH 6.8, 25°C
0.00193
2-(phenylmethylene)-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.00122 - 0.0154
2-chlorobenzaldehyde thiosemicarbazone
-
2.28
2-hydroxy-4-methoxybenzoic acid
Agaricus bisporus;
-
-
1.65
2-hydroxy-4-methylbenzoic acid
Agaricus bisporus;
-
-
7.9
2-hydroxy-5-methoxybenzoic acid
Agaricus bisporus;
-
-
2.15
2-hydroxy-5-methylbenzoic acid
Agaricus bisporus;
-
-
2.85
2-Hydroxybenzaldehyde
Agaricus bisporus;
-
-
4.3
2-hydroxybenzoic acid
Agaricus bisporus;
-
-
0.0749
2-hydroxyethyl (2E)-3-(5-hydroxy-4-oxo-4H-pyran-2-yl)prop-2-enoate
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.8), at 37°C
0.0004
2-hydroxytropone
Agaricus bisporus;
-
-
0.0981
2-methoxyethyl (2E)-3-(5-hydroxy-4-oxo-4H-pyran-2-yl)prop-2-enoate
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.8), at 37°C
2.6
2-Methylbenzaldehyde
Agaricus bisporus;
-
-
2.56
2-Methylbenzoic acid
Agaricus bisporus;
-
-
0.717 - 1.415
2-Methylresorcinol
15
2-oxoglutaric acid
Agaricus bisporus;
-
pH 7.0, 25°C
0.0153
2-[(1E,2E)-N-hydroxy-3-(pyridin-2-yl)prop-2-enimidoyl]phenol
Agaricus bisporus;
-
pH 6.8, 30°C
0.0127
2-[(1E,2E)-N-hydroxy-3-(pyridin-3-yl)prop-2-enimidoyl]phenol
Agaricus bisporus;
-
pH 6.8, 30°C
0.2
2-[(2,3,4-trihydroxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
IC50 above 0.2 mM, in 50 mM phosphate buffer (pH 6.8), at 25°C
0.00018
2-[(2,4-dihydroxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.0065
2-[(2,5-dihydroxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.0875
2-[(2,5-dimethoxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.00033
2-[(2-hydroxy-4-bromophenyl)methylene]thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.00038
2-[(2-hydroxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.1152
2-[(3,4,5-trihydroxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.1455
2-[(3,4,5-trimethoxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.0422
2-[(3,4-dihydroxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.0336
2-[(3,5-dihydroxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.00488
2-[(3-hydroxy-4-methoxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.0039
2-[(3-hydroxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.00568
2-[(3-methoxy-4-hydroxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.00028
2-[(4-bromophenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.00041
2-[(4-hydroxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.00148
2-[(4-methoxyphenyl)methylene]-thiosemicarbazone
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8), at 25°C
0.00073
2-[2-(2,4-dihydroxyphenyl)ethyl]-5-(D-xylopyranosyloxy)phenyl D-xylopyranoside
Agaricus bisporus;
-
-
0.0016
2-[2-(2,4-dihydroxyphenyl)ethyl]-5-hydroxyphenyl D-xylopyranoside
Agaricus bisporus;
-
5times more potent than that of kojic acid
0.0792
2-[2-(2-hydroxyethoxy)ethoxy]ethyl (2E)-3-(5-hydroxy-4-oxo-4H-pyran-2-yl)prop-2-enoate
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.8), at 37°C
0.0676
2-[2-(2-methoxyethoxy)ethoxy]ethyl (2E)-3-(5-hydroxy-4-oxo-4H-pyran-2-yl)prop-2-enoate
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.8), at 37°C
0.0000167
2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl (2E)-3-(2,4-dihydroxyphenyl)prop-2-enoate
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.0067
2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl (2E)-3-(4-chlorophenyl)prop-2-enoate
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.0065
2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.0077
2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl (2E)-3-phenylprop-2-enoate
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.0067
2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl 2,4-dihydroxybenzoate
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.0652
2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl 3,4,5-trihydroxybenzoate
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.0159
2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl 3,4-dihydroxybenzoate
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.0938
2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl 3,5-dihydroxybenzoate
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.0149
2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl 3-hydroxybenzoate, 2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl 4-hydroxybenzoate
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.001
2-[3-(2,4-dimethoxy-3-methylphenyl)propyl]benzene-1,4-diol
Agaricus bisporus;
-
-
0.00112
2alpha,3alpha,23-trihydroxyolean-12-en-28-oic acid
Agaricus bisporus;
-
-
0.0114
3'',4''-dihydroglabridin
Agaricus bisporus;
-
in 20 mM phosphate buffer (pH 6.8), at 25°C
0.555
3,4,5-trihydroxy-N-(3,4,5-trihydroxybenzyl)benzamide
Agaricus bisporus;
-
IC50: 0.555 mM
1.18
3,4,5-trihydroxy-N-(4-hydroxybenzyl)benzamide
Agaricus bisporus;
-
IC50: 1.180 mM
0.168 - 0.3
3,4-dihydroxy-4'-methoxydeoxybenzoin
0.28
3,4-dihydroxy-N-(3,4,5-trihydroxybenzyl)benzamide
Agaricus bisporus;
-
IC50: 0.280 mM
2
3,4-dihydroxy-N-(4-hydroxybenzyl)benzamide
Agaricus bisporus;
-
IC50: 2.0 mM
0.073
3,4-dihydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]benzamide
Mus musculus;
-
-
0.0003
3,4-dihydroxybenzaldehyde-O-ethyloxime
Agaricus bisporus;
-
-
0.97
3,4-dihydroxycinnamic acid
Agaricus bisporus;
-
-
1
3,4-dimethoxycinnamic acid
Agaricus bisporus;
-
IC50 above 1.0 mM in 0.1 M phosphate buffer (pH 7.0), at 37°C
1
3,4-dimethoxydihydrocinnamic acid
Agaricus bisporus;
-
IC50 above 1.0 mM in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.705
3,5-dihydroxy-N-(3,4,5-trihydroxybenzyl)benzamide
Agaricus bisporus;
-
IC50: 0.705 mM
0.71
3,5-dihydroxy-N-(4-hydroxybenzyl)benzamide
Agaricus bisporus;
-
IC50: 0.710 mM
0.55
3-(2-aminoethyl)-1H-indol-5-ol
Mus musculus;
-
-
0.27
3-(3',4',5'-trihydroxyphenyl)-6,8-dihydroxycoumarin
Agaricus bisporus;
-
in 0.067 M phosphoric acid buffer (pH 6.8), at 25°C
3.68
3-(3-hydroxyphenyl)-2H-chromen-2-one
Agaricus bisporus;
-
in 0.067 M phosphoric acid buffer (pH 6.8), at 25°C
0.016
3-hydroxy-1-methyl-1-phenylurea
Agaricus bisporus;
-
-
3.7
3-Hydroxybenzaldehyde
Agaricus bisporus;
-
-
1
3-hydroxycinnamic acid
Agaricus bisporus;
-
IC50 above 1 mM
0.0006 - 0.0634
3-hydroxyphloretin
0.03
3-hydroxyphlorizin
Homo sapiens;
-
the effect of the formosan apple constituents on hydroxyl radical-scavenging activity
1.8
3-Methoxybenzaldehyde
Agaricus bisporus;
-
-
0.45
3-methylbenzaldehyde
Agaricus bisporus;
-
-
0.58
3-methylbenzoic acid
Agaricus bisporus;
-
-
1.7
3-methylcrotonic acid
Agaricus bisporus;
-
-
0.01102
3beta, 23, 24-trihydroxyolean-12-en-28-oic acid
Agaricus bisporus;
-
-
0.1
4'-hydroxy-[1,1'-biphenyl]-2-carboxylic acid
Agaricus bisporus;
-
pH 6.5, 30°C
0.01059
4'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Agaricus bisporus;
-
pH 6.5, 30°C
0.0147
4'-hydroxy-[1,1'-biphenyl]-4-carboxylic acid
Agaricus bisporus;
-
pH 6.5, 30°C
0.1
4'-methoxy-[1,1'-biphenyl]-2-carboxylic acid
Agaricus bisporus;
-
above, pH 6.5, 30°C
0.0153
4'-methoxy-[1,1'-biphenyl]-3-carboxylic acid
Agaricus bisporus;
-
pH 6.5, 30°C
0.0153
4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid
Agaricus bisporus;
-
pH 6.5, 30°C
0.0024
4,4'-diamino-3-(4-hydroxyphenyl)-1'H-1,3'-bi-1,2,4-triazole-5,5'(4H,4'H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00101
4,4'-diamino-3-(pyridin-4-yl)-1'H-1,3'-bi-1,2,4-triazole-5,5'(4H,4'H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00037
4,4'-ethane-1,2-diyldibenzene-1,3-diol
Agaricus bisporus;
-
-
0.075
4-(1-methylethyl)benzaldehyde
Agaricus bisporus;
-
-
0.225
4-(1-methylethyl)benzoic acid
Agaricus bisporus;
-
-
0.049
4-(benzyloxy)-N'-(hydrazinylcarbonyl)benzohydrazide
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
1.15
4-(hexyloxy)benzoic acid
Agaricus bisporus;
-
-
1.4
4-(pentyloxy)benzoic acid
Agaricus bisporus;
-
-
0.215 - 4.13
4-Aminobenzoic acid
1.65
4-butoxybenzoic acid
Agaricus bisporus;
-
-
0.038
4-butylbenzaldehyde
Agaricus bisporus;
-
-
0.165 - 0.18
4-butylbenzoic acid
0.00182 - 0.0067
4-chlorobenzaldehyde thiosemicarbazone
-
0.1156
4-coumaric acid
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.00112
4-dodecylresorcinol
Pieris rapae;
-
reversible and competitive inhibition, IC50: 0.00112 mM
0.023
4-ethenylbenzaldehyde
Agaricus bisporus;
-
-
0.33
4-ethenylbenzoic acid
Agaricus bisporus;
-
-
1.1
4-ethoxybenzoic acid
Agaricus bisporus;
-
-
0.095
4-Ethylbenzaldehyde
Agaricus bisporus;
-
-
0.29
4-ethylbenzoic acid
Agaricus bisporus;
-
-
0.0019 - 0.00931
4-ethylresorcinol
0.0216
4-formyl-2-methoxyphenyl (4-methylpiperazin-1-yl)acetate
Agaricus bisporus;
-
pH 6.8, 25°C
0.1014
4-formyl-2-methoxyphenyl (4-phenylpiperazin-1-yl)acetate
Agaricus bisporus;
-
pH 6.8, 25°C
0.0789
4-formyl-2-methoxyphenyl chloroacetate
Agaricus bisporus;
-
pH 6.8, 25°C
3
4-formylphenyl 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranoside
Agaricus bisporus;
-
-
3
4-formylphenyl 2,3,4-tri-O-acetyl-beta-D-allopyranoside
Agaricus bisporus;
-
-
3
4-formylphenyl 2,3,4-tri-O-benzyl-beta-D-ribopyranoside
Agaricus bisporus;
-
-
3
4-formylphenyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-beta-D-glucopyranoside
Agaricus bisporus;
-
-
0.62
4-formylphenyl 2,3-O-(1-methylethylidene)-beta-D-allopyranoside
Agaricus bisporus;
-
-
0.052
4-formylphenyl 4,6-O-(phenylmethylidene)-beta-D-gulopyranoside
Agaricus bisporus;
-
-
0.43
4-formylphenyl 6-O-(dimethoxyphosphoryl)-beta-D-allopyranoside
Agaricus bisporus;
-
-
3
4-formylphenyl 6-O-trityl-beta-D-allopyranoside
Agaricus bisporus;
-
-
2.54
4-formylphenyl beta-D-allopyranoside
Agaricus bisporus;
-
-
0.94
4-formylphenyl beta-D-glucopyranoside
Agaricus bisporus;
-
-
0.28
4-formylphenyl beta-D-ribopyranoside
Agaricus bisporus;
-
-
2.54
4-formylphenyl-O-beta-D-allopyranoside
Agaricus bisporus;
-
-
0.0088
4-heptylbenzaldehyde
Agaricus bisporus;
-
-
0.075 - 0.095
4-heptylbenzoic acid
0.008
4-hexylbenzaldehyde
Agaricus bisporus;
-
-
0.106 - 0.11
4-hexylbenzoic acid
0.0025 - 0.018
4-hexylresorcinol
0.97
4-hydroxy-3-methoxycinnamic acid
Agaricus bisporus;
-
-
0.211
4-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-methoxybenzamide
Mus musculus;
-
-
0.233
4-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]benzamide
Mus musculus;
-
-
1.12 - 1.22
4-hydroxybenzaldehyde
1.3
4-hydroxybenzoic acid
Agaricus bisporus;
-
-
3
4-hydroxyphenyl beta-D-xyloside
Agaricus bisporus;
-
in 100 mM sodium phosphate buffer (pH 6.8), at 25°C
0.74
4-hydroxyphenyl beta-xylodioside
Agaricus bisporus;
-
in 100 mM sodium phosphate buffer (pH 6.8), at 25°C
0.18
4-hydroxyphenyl beta-xylotetraoside
Agaricus bisporus;
-
in 100 mM sodium phosphate buffer (pH 6.8), at 25°C
0.48
4-hydroxyphenyl beta-xylotrioside
Agaricus bisporus;
-
in 100 mM sodium phosphate buffer (pH 6.8), at 25°C
0.35
4-methoxybenzaldehyde
Agaricus bisporus;
-
-
0.42
4-methoxybenzoic acid
Agaricus bisporus;
-
-
0.41 - 0.8617
4-methoxycinnamic acid
0.12
4-methylbenzaldehyde
Agaricus bisporus;
-
-
0.35
4-methylbenzoic acid
Agaricus bisporus;
-
-
0.0011
4-methylresorcinol
Agaricus bisporus;
-
pH 7.0, 25°C, inhibition of the diphenolase activity of mushroom tyrosinase
0.01
4-octylbenzaldehyde
Agaricus bisporus;
-
-
0.047 - 0.082
4-octylbenzoic acid
0.0135
4-pentylbenzaldehyde
Agaricus bisporus;
-
-
0.12 - 0.152
4-pentylbenzoic acid
0.8 - 1.1
4-phenyl-2-butanol
1.85
4-propoxybenzoic acid
Agaricus bisporus;
-
-
0.075
4-propylbenzaldehyde
Agaricus bisporus;
-
-
0.213 - 0.235
4-propylbenzoic acid
0.038
4-tert-butylbenzaldehyde
Agaricus bisporus;
-
-
0.215
4-tert-butylbenzoic acid
Agaricus bisporus;
-
-
0.00341
4-[(E)-(carbamothioylhydrazono)methyl]phenyl 2,3,4,6-tetra-O-acetyl-beta-D-allopyranoside
Agaricus bisporus;
-
-
0.00041
4-[(E)-(carbamothioylhydrazono)methyl]phenyl 2,3,4,6-tetra-O-acetyl-beta-D-galactopyranoside
Agaricus bisporus;
-
-
0.00031
4-[(E)-(carbamothioylhydrazono)methyl]phenyl 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranoside
Agaricus bisporus;
-
-
0.0528
4-[(E)-(carbamothioylhydrazono)methyl]phenyl 2,3,4,6-tetrakis-O-(phenylcarbonyl)-beta-D-glucopyranoside
Agaricus bisporus;
-
-
0.0365
4-[(E)-(carbamothioylhydrazono)methyl]phenyl 2,3,4-tris-O-(phenylcarbonyl)-beta-D-xylopyranoside
Agaricus bisporus;
-
-
0.00065
4-[(E)-(carbamothioylhydrazono)methyl]phenyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-beta-D-glucopyranoside
Agaricus bisporus;
-
-
0.00361
4-[(E)-(carbamothioylhydrazono)methyl]phenyl beta-D-allopyranoside
Agaricus bisporus;
-
-
0.00296
4-[(E)-(carbamothioylhydrazono)methyl]phenyl beta-D-glucopyranoside
Agaricus bisporus;
-
-
0.2
4-[(E)-(hydroxyimino)methyl]phenyl 2,3,4,6-tetra-O-acetyl-beta-D-allopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(hydroxyimino)methyl]phenyl 2,3,4,6-tetra-O-acetyl-beta-D-galactopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(hydroxyimino)methyl]phenyl 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(hydroxyimino)methyl]phenyl 2,3,4,6-tetrakis-O-(phenylcarbonyl)-beta-D-glucopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(hydroxyimino)methyl]phenyl 2,3,4-tris-O-(phenylcarbonyl)-beta-D-xylopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(hydroxyimino)methyl]phenyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-beta-D-glucopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(hydroxyimino)methyl]phenyl beta-D-allopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(hydroxyimino)methyl]phenyl beta-D-glucopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(methoxyimino)methyl]phenyl 2,3,4,6-tetra-O-acetyl-beta-D-allopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(methoxyimino)methyl]phenyl 2,3,4,6-tetra-O-acetyl-beta-D-galactopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(methoxyimino)methyl]phenyl 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(methoxyimino)methyl]phenyl 2,3,4,6-tetrakis-O-(phenylcarbonyl)-beta-D-glucopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(methoxyimino)methyl]phenyl 2,3,4-tris-O-(phenylcarbonyl)-beta-D-xylopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(methoxyimino)methyl]phenyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-beta-D-glucopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(methoxyimino)methyl]phenyl beta-D-allopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.2
4-[(E)-(methoxyimino)methyl]phenyl beta-D-glucopyranoside
Agaricus bisporus;
-
IC50 above 0.2 mM
0.00043
4-[2-(2,4-dihydroxyphenyl)ethyl]-3-hydroxyphenyl D-xylopyranoside
Agaricus bisporus;
-
-
0.024
4-[3-(2-hydroxy-5-methoxyphenyl)propyl]benzene-1,3-diol
Agaricus bisporus;
-
-
0.0027 - 0.0238
4-[[hydroxy(nitroso)amino]methyl]benzene-1,3-diol
0.0011 - 0.0137
4-[[hydroxy(nitroso)amino]methyl]phenol
0.0185
5'-(3-hydroxyphenyl)-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00177
5'-(4-hydroxyphenyl)-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00019
5'-(4-hydroxyphenyl)-2,3'-bi-1,3,4-thiadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00053
5'-(4-[[tert-butyl(dimethyl)silyl]oxy]phenyl)-2,3'-bi-1,3,4-thiadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00676
5'-(diphenylmethyl)-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.0052
5'-(diphenylmethyl)-2,3'-bi-1,3,4-thiadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.0336
5'-(naphthalen-1-yl)-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.0142
5'-(pyridin-4-yl)-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00247
5'-(pyridin-4-yl)-2,3'-bi-1,3,4-thiadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00367
5'-benzyl-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00494
5'-cyclohexyl-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00647
5'-phenyl-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00131
5'-phenyl-2,3'-bi-1,3,4-thiadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00442
5'-[(5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)methyl]-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00049
5'-[(5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)methyl]-2,3'-bi-1,3,4-thiadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.0019
5'-[3-(5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl]-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00364
5'-[3-(benzyloxy)phenyl]-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00135
5'-[4-(benzyloxy)phenyl]-2,3'-bi-1,3,4-oxadiazole-2',5(4H)-dithione
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.00026 - 0.01861
5,2',4'-trihydroxy-2'',2''-dimethylchromene-(6,7:5'',6'')-flavanone
0.1325
5-(4-(2-(2-methoxyethoxy)ethoxy)benzyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.2
5-(4-(2-(2-methoxyethoxy)ethoxy)benzyl)pyrimidine-2,4,6(1H,3H,5H)trione
Agaricus bisporus;
-
IC50 above 0.2 mM, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.0342
5-(4-(2-(2-methoxyethoxy)ethoxy)benzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.1374
5-(4-(2-(2-methoxyethoxy)ethoxy)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.1793
5-(4-(2-butoxyethoxy)benzyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.1074
5-(4-(2-butoxyethoxy)benzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.04545
5-(4-(2-butoxyethoxy)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.1559
5-(4-(2-hydroxyethoxy)benzyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.2
5-(4-(2-hydroxyethoxy)benzyl)pyrimidine-2,4,6(1H,3H,5H)-trione
Agaricus bisporus;
-
IC50 above 0.2 mM, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.2
5-(4-(2-hydroxyethoxy)benzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
IC50 above 0.2 mM, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.2
5-(4-(2-hydroxyethoxy)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
Agaricus bisporus;
-
IC50 above 0.2 mM, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.1128
5-(4-(2-methoxyethoxy)benzyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.2
5-(4-(2-methoxyethoxy)benzyl)pyrimidine-2,4,6(1H,3H,5H)-trione
Agaricus bisporus;
-
IC50 above 0.2 mM, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.02843
5-(4-(2-methoxyethoxy)benzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.07542
5-(4-(2-methoxyethoxy)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.2
5-(4-(4-methoxy)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
Agaricus bisporus;
-
IC50 above 0.2 mM, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.2
5-(4-(4-methoxybutoxy)benzyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
IC50 above 0.2 mM, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.2
5-(4-(4-methoxyethoxy)benzyl)pyrimidine-2,4,6(1H,3H,5H)-trione
Agaricus bisporus;
-
IC50 above 0.2 mM, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.0778
5-(4-(4-methoxyethoxy)benzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.07002
5-(4-hydroxybenzyl)-2-thioxo-dihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.2
5-(4-hydroxybenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione
Agaricus bisporus;
-
IC50 above 0.2 mM, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.01449
5-(4-hydroxybenzylidene)-2-thioxo-dihydropyrimidine-4,6(1H,5H)-dione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.01398
5-(4-hydroxybenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
Agaricus bisporus;
-
in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 25°C
0.0514 - 0.0516
5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one
0.98
5-hydroxymethyl-2-furfural
Agaricus bisporus;
-
-
0.0422
6-hydroxy-2H-pyran-3-carbaldehyde
Agaricus bisporus;
-
-
1.567
6-hydroxy-3-(4'-hydroxyphenyl)coumarin
Agaricus bisporus;
-
in 0.067 M phosphoric acid buffer (pH 6.8), at 25°C
0.193
6-hydroxyapigenin
Agaricus bisporus;
-
-
0.182
6-hydroxygalangin
Agaricus bisporus;
-
-
0.124
6-hydroxykaempferol
Agaricus bisporus;
-
-
0.1
7-hydroxy-3-(4-hydroxyphenyl)-2H-chromen-2-one
Agaricus bisporus;
-
IC50 above 0.1 mM, in 0.067 M phosphoric acid buffer (pH 6.8), at 25°C
0.0442 - 0.2
8-isoprenyl-5'-geranyl-5,7,2',4'-tetrahydroxy flavanone
0.312
8-O-methyltianmushanol
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 37°C
0.2
9-hydroxy-4-methoxypsoralen
Agaricus bisporus;
-
-
0.00078
Ac-KSRFR
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.00081
Ac-KSSFR
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.00075
Ac-RSRFK
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.00029
Ac-RSRFS
Agaricus bisporus;
-
pH 6.8, 25°C
-
0.85
acetophenone
Agaricus bisporus;
-
-
0.03
Agaritine
Agaricus bisporus;
-
-
0.0985 - 0.2
albafuran A
0.1
aloesin
Agaricus bisporus;
-
-
12
alpha-picolyl heptyl amine
Agaricus bisporus;
-
IC50 above 12 mM, in 0.1 M phosphate buffer (pH 6.5)
-
12
alpha-picolyl pentyl amine
Agaricus bisporus;
-
IC50 above 12 mM, in 0.1 M phosphate buffer (pH 6.5)
12
alpha-picolyl propyl amine
Agaricus bisporus;
-
IC50 above 12 mM, in 0.1 M phosphate buffer (pH 6.5)
0.0075 - 0.028
ammonium tetramolybdate
0.0001
anacardic acid
Agaricus bisporus;
-
-
0.38
Anisaldehyde
Agaricus bisporus;
-
-
0.68
Anisic acid
Agaricus bisporus;
-
-
0.04 - 548
arbutin
0.006577
arjungenin
Agaricus bisporus;
-
-
0.001
arjunilic acid
Agaricus bisporus;
-
-
0.001545
artocarpanone
Agaricus bisporus;
-
-
0.0005254
artocarpesin
Agaricus bisporus;
-
-
0.2009
artocarpetin
Agaricus bisporus;
-
-
0.04793
artocarpfuranol
Agaricus bisporus;
-
-
0.03 - 4.61
ascorbic acid
0.273
baicalein
Agaricus bisporus;
-
-
0.0011
bayogenin
Agaricus bisporus;
-
-
0.8
benzaldehyde
Agaricus bisporus;
-
-
0.9 - 10.2
Benzoic acid
0.6 - 2.8
benzylacetone
1.5 - 2
benzylideneacetone
-
6.3
beta-arbutin
Agaricus bisporus;
-
-
0.49
beta-mercaptoethanol
Lactarius salmonicolor;
-
at 25°C
9.5
beta-picolyl heptyl amine
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.5)
12
beta-picolyl pentyl amine
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.5)
12
beta-picolyl propyl amine
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.5)
1.44
betulin
Agaricus bisporus;
-
-
0.00214
betulinic acid
Agaricus bisporus;
-
-
25
Bromoacetate
Agaricus bisporus;
-
-
0.06028
brosimone I
Agaricus bisporus;
-
-
0.00043 - 0.00057
broussonin C
0.35
bufobutanoic acid
Agaricus bisporus;
-
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.4 - 1
caffeic acid
0.0089
campestrol
Agaricus bisporus;
-
isolated from Trifolium balansae, NMR structure identification, IC50: 0.00890 mM
0.09438
carpachromene
Agaricus bisporus;
-
-
0.0011 - 0.022
catechol
0.02 - 7
cefazolin
0.13 - 0.21
cefodizime
0.045
chrysin
Homo sapiens;
-
the effect of the formosan apple constituents on hydroxyl radical-scavenging activity
1
Cinnamic acid
62.91
Citric acid
Lactuca sativa;
-
-
155 - 164
Cl-
0.1666
cudraflavone B
Agaricus bisporus;
-
-
0.26
cumic acid
Agaricus bisporus;
-
-
0.05
cuminaldehyde
Agaricus bisporus;
-
-
0.06873
cyanomaclurin
Agaricus bisporus;
-
-
0.092
cyclomorusin
Agaricus bisporus;
-
for monophenolase activity
0.58
D-ascorbic acid-6-p-hydroxybenzoic acid ester
Agaricus bisporus;
-
in 50 mM phosphate buffer (pH 6.8) for 10 min at 25°C
0.194
daedalin A
Agaricus bisporus;
-
-
1
dihydro-4-coumaric acid
Agaricus bisporus;
-
IC50 above 1.0 mM in 0.1 M phosphate buffer (pH 7.0), at 37°C
1
dihydro-4-methoxycinnamic acid
Agaricus bisporus;
-
IC50 above 1.0 mM in 0.1 M phosphate buffer (pH 7.0), at 37°C
1
dihydrocaffeic acid
Agaricus bisporus;
-
IC50 above 1.0 mM in 0.1 M phosphate buffer (pH 7.0), at 37°C
1
dihydrocinnamic acid
Agaricus bisporus;
-
IC50 above 1.0 mM in 0.1 M phosphate buffer (pH 7.0), at 37°C
1
dihydroferulic acid
Agaricus bisporus;
-
IC50 above 1.0 mM in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.1957
dihydroisoferulic acid
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.01035
dihydromorin
Agaricus bisporus;
-
-
1
dihydrosinapic acid
Agaricus bisporus;
-
IC50 above 1.0 mM in 0.1 M phosphate buffer (pH 7.0), at 37°C
2350
DMSO
Neobellieria bullata;
-
at 30°C
26.4
EDTA
Lactuca sativa;
-
-
0.0655
epigallocatechin gallate
Agaricus bisporus;
-
-
0.00312
erythrodiol
Agaricus bisporus;
-
-
0.21 - 0.225
esculetin
0.0363
ethyl (2E)-3-(5-hydroxy-4-oxo-4H-pyran-2-yl)prop-2-enoate
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.8), at 37°C
0.11
farnesic acid
Agaricus bisporus;
-
-
1
ferulic acid
Agaricus bisporus;
-
IC50 above 1.0 mM in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.00179 - 0.00748
flemichin D
0.00101 - 0.0195
fleminchalcone A
0.0184 - 0.0326
fleminchalcone B
0.00128 - 0.00522
fleminchalcone C
6.8
gamma-picolyl heptyl amine
Agaricus bisporus;
-
-
4.2
gamma-picolyl pentyl amine
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.5)
5.8
gamma-picolyl propyl amine
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.5)
1.62
geranial
Agaricus bisporus;
-
-
0.01858
glabridin
Agaricus bisporus;
-
in 20 mM phosphate buffer (pH 6.8), at 25°C
0.0114 - 4.7
glutathione
16.08
hesperidin
Agaricus bisporus;
-
-
3.35 - 13.2
hexanoic acid
0.01348 - 1.09
hydroquinone
0.0006628
isoartocarpesin
Agaricus bisporus;
-
-
0.1149
isoferulic acid
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.23 - 0.262
kaempferol
0.0155 - 0.0228
kazinol C
0.1647 - 0.2
kazinol D
0.00096 - 0.0017
kazinol F
0.0179 - 0.0269
kazinol S
0.1031 - 0.2
kazinol T
3.6
KFEKKFEK
Agaricus bisporus;
-
in 0.67 mM potassium phosphate buffer (pH 6.8), at 37°C
0.00496 - 0.0204
khonklonginol H
0.0074 - 0.7
kojic acid
0.88
kuraridinol
Agaricus bisporus;
-
potent tyrosinase inhibitory activity
0.0001 - 8.6
kurarinol
0.0022
kurarinone
Agaricus bisporus;
-
-
0.1318 - 0.2
kuwanon A
0.135
kuwanon C
Agaricus bisporus;
-
for monophenolase activity
0.0475 - 0.2
kuwanon E
0.2
kuwanon U
Agaricus bisporus;
-
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C; IC50 above 0.2 mM, using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C
0.0204 - 10.39
L-cysteine
0.00368
L-mimosine
3.56 - 16
L-phenylalanine
2.73
L-Pro-L-Leu-Gly
Agaricus bisporus;
-
in 0.67 mM potassium phosphate buffer (pH 6.8), at 37°C
0.00038
L-tyrosine
Lactarius salmonicolor;
-
at 25°C
2.24
lupeol
Agaricus bisporus;
-
-
0.0112 - 0.0841
lupinifolin
0.0017
maslinic acid
Agaricus bisporus;
-
-
0.04 - 0.047
Methimazole
0.349
methyl (Z)-2-((E)-2-(((E)-(5-bromothiophen-2-yl)methylene)hydrazono)-4-oxothiazolidin-5-ylidene)acetate
Agaricus bisporus;
-
pH 6.8, 25°C, substrate L-DOPA
0.101
methyl (Z)-2-((E)-2-(((E)-4-(dimethylamino)benzylidene)hydrazono)-4-oxothiazolidin-5-ylidene)acetate
Agaricus bisporus;
-
pH 6.8, 25°C, substrate L-DOPA
0.002345
methyl arjunolate
Agaricus bisporus;
-
-
0.0074 - 0.0646
moracin M
0.1603 - 0.2
moracin N
0.0825 - 0.2
moracinoside M
2.32
morin
0.088
mormin
Agaricus bisporus;
-
for monophenolase activity
0.25
morusin
Agaricus bisporus;
-
for monophenolase activity
0.2
morusinol
Agaricus bisporus;
-
IC50 above 0.2 mM, using L-DOPA as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C; IC50 above 0.2 mM, using L-tyrosine as substrate, in 0.25 M phosphate buffer (pH 6.8), at 30°C
0.027
N',N'''-benzene-1,4-diylbis(1-hydroxyurea)
Agaricus bisporus;
-
-
0.1772
N'-(hydrazinylcarbonyl)-4-hydroxybenzohydrazide
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.996
N'-(hydrazinylcarbonyl)naphthalene-2-carbohydrazide
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 25°C
0.17 - 0.23
N,N-unsubstituted selenourea derivatives
Agaricus bisporus;
-
55.5% inhibition at 0.2 mM, IC50: 0.17-0.23 mM
-
0.029
N-(2,4-dihydroxybenzyl)-2,4-dihydroxybenzamide
Agaricus bisporus;
-
IC50: 0.029 mM
0.017
N-(2,4-dihydroxybenzyl)-3,4,5-trihydroxybenzamide
Agaricus bisporus;
-
IC50: 0.017 mM
0.011
N-(2,4-dihydroxybenzyl)-3,4-dihydroxybenzamide
Agaricus bisporus;
-
IC50: 0.011 mM
0.0022
N-(2,4-dihydroxybenzyl)-3,5-dihydroxybenzamide
Agaricus bisporus;
-
IC50: 0.0022 mM
1.66
N-benzyl-2,4-dihydroxybenzamide
Agaricus bisporus;
-
IC50: 1.660 mM
0.78
N-benzyl-3,4,5-trihydroxybenzamide
Agaricus bisporus;
-
IC50: 0.780 mM
2
N-benzyl-3,4-dihydroxybenzamide
Agaricus bisporus;
-
IC50: 2.0 mM
0.7
N-benzyl-3,5-dihydroxybenzamide
Agaricus bisporus;
-
IC50: 0.700 mM
1.99
N-benzylamide
Agaricus bisporus;
-
IC50: 1.990 mM
0.028
N-caffeoylserotonin
Mus musculus;
-
in 50 mM phosphate buffer (pH 6.8), at 37°C
0.17
N-hydroxy-N-(phenylcarbamoyl)acetamide
Agaricus bisporus;
-
-
0.0018
N-phenylthiourea
Agaricus bisporus;
-
-
0.073
N-protocatechuoylserotonin
Mus musculus;
-
in 50 mM phosphate buffer (pH 6.8), at 37°C
0.311
N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide
Mus musculus;
-
-
0.333
N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]benzamide
Mus musculus;
-
-
16.84
NaF
Litchi chinensis;
-
-
0.1274 - 0.2
neocyclomorusin
1.49
nobiletin
Agaricus bisporus;
-
-
0.0012 - 0.4647
norartocarpetin
2.15 - 3.06
Octanoic acid
0.4
octyl (2E)-3-(5-hydroxy-4-oxo-4H-pyran-2-yl)prop-2-enoate
Agaricus bisporus;
-
in 0.1 M phosphate buffer (pH 6.8), at 37°C
0.12
oxalic acid
Lactarius salmonicolor;
-
at 25°C
0.001 - 0.0012
oxyresveratrol
0.23
p-aminobenzenesulfonamide
Lactarius salmonicolor;
-
at 25°C
0.2 - 3.65
p-coumaric acid
4.54
p-hydroxybenzoic acid
Lactuca sativa;
-
-
0.3506
p-hydroxybenzyl alcohol
Agaricus bisporus;
-
-
0.00017 - 0.17
Phenylthiourea
0.0008
phloretin
Homo sapiens;
-
the effect of the formosan apple constituents on hydroxyl radical-scavenging activity. Phloretin, quercetin, 3-hydroxyphloretin, catechol, and pinosylvin have the strongest hydroxyl radical-scavenging properties
0.087
phloridzin
Homo sapiens;
-
the effect of the formosan apple constituents on hydroxyl radical-scavenging activity
0.0025
pinosylvin
Homo sapiens;
-
the effect of the formosan apple constituents on hydroxyl radical-scavenging activity, phloretin, quercetin, 3-hydroxyphloretin, catechol, and pinosylvin have the strongest hydroxyl radical-scavenging properties
0.346
procyanidin B1
Agaricus bisporus;
-
-
0.042
protocatechuic acid
Homo sapiens;
-
the effect of the formosan apple constituents on hydroxyl radical-scavenging activity
0.0012 - 0.07
quercetin
0.123
RADSRADC
Agaricus bisporus;
-
in 0.67 mM potassium phosphate buffer (pH 6.8), at 37°C
0.652 - 1.125
resorcinol
0.08
rutin
Homo sapiens;
-
the effect of the formosan apple constituents on hydroxyl radical-scavenging activity
0.0008 - 0.0012
Salicylhydroxamic acid
0.35
serotonin
Agaricus bisporus;
-
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C
8
SFLLRN
Agaricus bisporus;
-
in 0.67 mM potassium phosphate buffer (pH 6.8), at 37°C
1
Sinapic acid
Agaricus bisporus;
-
IC50 above 1.0 mM in 0.1 M phosphate buffer (pH 7.0), at 37°C
0.05 - 13.8
Sodium azide
0.06 - 41
Sodium metabisulfite
0.0047
sophoraflavanone G
Agaricus bisporus;
-
-
1.13
soyacerebroside I
Agaricus bisporus;
-
-
0.0005733 - 0.0265
steppogenin
0.00239
stigmast-5-ene-3beta,26-diol
Agaricus bisporus;
-
isolated from Trifolium balansae, NMR structure identification, IC50: 0.00239 mM
0.00525
stigmast-5-ene-3beta-ol
Agaricus bisporus;
-
isolated from Trifolium balansae, NMR structure identification, IC50: 0.00525 mM
0.4
syringic acid
Lactarius salmonicolor;
-
at 25°C
2
Thiosemicarbazide
0.008 - 1.73
Thiourea
0.358
tianmushanol
Agaricus bisporus;
-
in 50 mM Na-phosphate buffer (pH 6.8), at 37°C
0.85
trans-cinnamaldehyde
Agaricus bisporus;
-
-
0.14 - 2.3
trans-geranic acid
506.8
trifolirhizin
Agaricus bisporus;
-
moderate inhibitory activity
0.0004 - 0.413
tropolone
0.42
umbelliferone
Agaricus bisporus;
-
in 0.067 M phosphoric acid buffer (pH 6.8), at 25°C
0.04
YRSRKYSSWY
Agaricus bisporus;
-
in 0.67 mM potassium phosphate buffer (pH 6.8), at 37°C
0.00697
[1,1''-biphenyl]-3-carboxylic acid
Agaricus bisporus;
-
pH 6.5, 30°C
-
0.1
[1,1'-biphenyl]-2-carboxylic acid
Agaricus bisporus;
-
above, pH 6.5, 30°C
0.06324
[1,1'-biphenyl]-4-carboxylic acid
Agaricus bisporus;
-
pH 6.5, 30°C
0.0753
[2-(furan-2-ylmethylene-hydrazono)-4-oxo-thiazolidin-5-ylidene]-acetic acid methyl ester
Agaricus bisporus;
-
pH 6.8, 25°C, substrate L-DOPA
-
0.142
[2-[(4-benzyloxy-benzylidene)-hydrazono]-4-oxo-thiazolidin-5-ylidene]-acetic acid methyl ester
Agaricus bisporus;
-
pH 6.8, 25°C, substrate L-DOPA
0.0032
[4-oxo-2-(pyridin-4-ylmethylene-hydrazono)-thiazolidin-5-ylidene]-acetic acid methyl ester
Agaricus bisporus;
-
pH 6.8, 25°C, substrate L-DOPA
additional information
additional information
-