1.14.17.3: peptidylglycine monooxygenase
This is an abbreviated version!
For detailed information about peptidylglycine monooxygenase, go to the full flat file.
Word Map on EC 1.14.17.3
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1.14.17.3
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glycine-extended
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neuropeptides
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beta-monooxygenase
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peptidyl-alpha-hydroxyglycine
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prohormone
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alpha-hydroxyglycine
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peptidylamidoglycolate
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endoproteolytic
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neurointermediate
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corticotrope
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ascorbate-dependent
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exafs
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4.3.2.5
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4-phenyl-3-butenoic
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noncoupled
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side-on
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dbetam
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medicine
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analysis
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synthesis
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pharmacology
- 1.14.17.3
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glycine-extended
- neuropeptides
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beta-monooxygenase
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peptidyl-alpha-hydroxyglycine
-
prohormone
- alpha-hydroxyglycine
- peptidylamidoglycolate
-
endoproteolytic
-
neurointermediate
-
corticotrope
-
ascorbate-dependent
-
exafs
-
4.3.2.5
-
4-phenyl-3-butenoic
-
noncoupled
-
side-on
- dbetam
- medicine
- analysis
- synthesis
- pharmacology
Reaction
Synonyms
alpha-AE, bifunctional PAM, bifunctional peptidylglycine alpha-amidating monooxygenase, CG3832, hPHMcc, More, PAM, PAM-1, PAM-2, PAM-A, PAM-B, PAM/PHM, peptide alpha-amidating enzyme, peptide alpha-amide synthase, peptide-alpha-amide synthetase, peptidyl alpha-amidating enzyme, peptidyl alpha-hydroxylating monooxygenase, peptidyl-glycine alpha-amidating monooxygenase, peptidylglycine 2-hydroxylase, peptidylglycine alpha-amidating mono-oxygenase, peptidylglycine alpha-amidating monooxygenase, peptidylglycine alpha-hydroxylase, peptidylglycine alpha-hydroxylating monooxygenase, peptidylglycine alpha-hydroxylating-monooxygenase, peptidylglycine alpha-monooxygenase, peptidylglycine monooxygenase, peptidylglycine-alpha-amidating monooxygenase, PHM, PHMcc, synthase, peptide alpha-amide, type A PAM
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1.14.17.3 peptidylglycine monooxygenaseAdvanced search results
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results (Synonyms
Synonyms on EC 1.14.17.3 - peptidylglycine monooxygenase
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
alpha-AE
bifunctional peptidylglycine alpha-amidating monooxygenase
PAM
PAM-1
PAM-A
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PAM-B
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peptide alpha-amidating enzyme
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peptide alpha-amide synthase
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peptide-alpha-amide synthetase
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peptidyl alpha-amidating enzyme
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peptidyl alpha-hydroxylating monooxygenase
peptidylglycine 2-hydroxylase
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peptidylglycine alpha-amidating monooxygenase
peptidylglycine alpha-hydroxylase
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peptidylglycine alpha-hydroxylating monooxygenase
peptidylglycine alpha-monooxygenase
peptidylglycine monooxygenase
peptidylglycine-alpha-amidating monooxygenase
PHM
synthase, peptide alpha-amide
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additional information
PAM
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PAM
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PAM consists of O2-sensitive PHM and peptidyl-alpha-hydroxyglycine alpha-amidating lyase, PAL, activities
PAM
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PAM consists of O2-sensitive PHM and peptidyl-alpha-hydroxyglycine alpha-amidating lyase, PAL, activities
peptidylglycine alpha-amidating monooxygenase
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peptidylglycine alpha-amidating monooxygenase
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peptidylglycine alpha-amidating monooxygenase
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two catalytic domains: peptidylglycine alpha-hydroxylating monooxygenase and peptidyl-alpha-hydroxyglycine alpha-amidating lyase
peptidylglycine alpha-amidating monooxygenase
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bifunctional enzyme: peptidylglycine alpha-hydroxylating monooxygenase and peptigylamidoglycolate lyase
peptidylglycine alpha-hydroxylating monooxygenase
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subunit of bifunctional peptidylglycine alpha-amidating monooxygenase (PAM)
peptidylglycine alpha-hydroxylating monooxygenase
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peptidylglycine alpha-hydroxylating monooxygenase
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peptidylglycine alpha-hydroxylating monooxygenase
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the bifunctional enzyme peptidylglycine alpha-amidating monooxygenase possesses two different catalytic domains: the peptidylglycine alpha-hydroxylating monooxygenase domain and the peptidyl alpha-hydroxyglycine alpha-amidating lyase domain
additional information
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EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
additional information
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EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
additional information
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EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
additional information
-
EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
additional information
-
EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
additional information
-
EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
additional information
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the 2-step process is catalyzed by only 1 enzyme called type A peptidylglycine alpha-amidating enzyme
additional information
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the 2-step process is catalyzed by only 1 enzyme called type A peptidylglycine alpha-amidating enzyme
additional information
-
the 2-step process is catalyzed by only 1 enzyme called type A peptidylglycine alpha-amidating enzyme
additional information
the 2-step process is catalyzed by only 1 enzyme called type A peptidylglycine alpha-amidating enzyme
additional information
-
EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
additional information
-
EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
additional information
-
EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
additional information
-
EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
additional information
-
EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL)
