1.14.16.7: phenylalanine 3-monooxygenase
This is an abbreviated version!
For detailed information about phenylalanine 3-monooxygenase, go to the full flat file.
Reaction
Synonyms
PacX, phenylalanine 3-hydroxylase
ECTree
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Substrates Products
Substrates Products on EC 1.14.16.7 - phenylalanine 3-monooxygenase
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REACTION DIAGRAM
L-phenylalanine + 6-methyltetrahydropterin + O2
3-hydroxy-L-phenylalanine + 4a-hydroxy-6-methyltetrahydropterin
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L-phenylalanine + tetrahydrobiopterin + O2
3-hydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin
the enzyme forms 3-hydroxy-L-phenylalanine (i.e. m-L-tyrosine) which is one of the building blocks in the biosynthesis of pacidamycins
3-hydroxy-L-phenylalanine i.e. m-L-Tyr
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additional information
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no activity with D-Phe, L-Tyr, and L-Trp
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