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1.14.16.6: mandelate 4-monooxygenase

This is an abbreviated version!
For detailed information about mandelate 4-monooxygenase, go to the full flat file.

Reaction

(S)-2-Hydroxy-2-phenylacetate
+
a 5,6,7,8-tetrahydropteridine
+
O2
=
(S)-4-hydroxymandelate
+
a 4a-hydroxy-5,6,7,8-tetrahydropteridine

Synonyms

L-mandelate-4-hydroxylase, mandelic acid 4-hydroxylase, oxygenase, mandelate 4-mono-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.16.6 mandelate 4-monooxygenase

Activating Compound

Activating Compound on EC 1.14.16.6 - mandelate 4-monooxygenase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-amino-4-hydroxy-6,7-dimethyl-tetrahydropteridine
tetrahydrofolic acid
-
pteridine cofactor required, 50% of the activity of 2-amino-4-hydroxy-6,7-dimethyl-tetrahydropteridine
tetrahydropteridine
-
required